Watson (2024) s02e06 Episode Script
Buying Time
1
- (BREATHING DEEPLY)
- RIA (MUFFLED): Casey.
(PULSE BEATING)
Casey?
(CLEARLY): Casey?
You're here again. What's wrong?
Yeah, it's just, it's my back.
It-It's getting worse, and
and now I got these-these headaches,
this throbbing in my ears,
and nothing's drowning it out.
Hey, you need a hospital.
I need a hospital.
I need insurance.
I need a lot of things.
Okay, wait here, Casey.
I'll find a doctor.
This morning's numbers, Mr. Bell.
Ranger, my name is Joseph.
I keep telling you that.
These numbers are good.
I've got the liver of a 22-year-old,
kidneys tracking at 25.
We should make a post for socials.
Tell Kristen to write up a script.
CLERK: Number 92, please.
The doctor's ready to see you.
Number 92.
Do you want me to confirm
your interview at 1100?
I doubt the doctor
would call it an interview.
I hear the man's got an ego.
But confirm.
And get the car ready and come back.
- Yes, sir.
- RIA: I'm so sorry, we're short-staffed,
Casey. Listen,
you could be having a stroke,
an aneurysm, a hemorrhage.
The point is, I don't know.
I'm just a volunteer.
They can't turn you away from an ER.
You need tests,
imaging, an MRI probably.
There's what I need and
there's what I can afford, man.
I know about a place.
A girl I used to see at Pitt
she works there.
Insurance, your ability to pay
it's not always their first concern.
What-What's the place?
- (INDISTINCT ARGUMENT)
- One second, all right?
Car's ready, sir.
Remind me what
I'm putting into the GPS.
BOTH: It's called the Holmes Clinic.
Okay. Thank you.
What kind of name is Ranger?
My father wanted me
to be an Army Ranger.
A Ranger named Ranger.
So, did you make the cut?
Three tours. And you?
Where'd you get your training?
The High Down
Youth Offender Institution.
More of an informal program, really.
JOSEPH: Aging is a disease.
Do you agree, Dr. Watson?
I agree that it sounds catchy.
It's more than that.
This is critical work.
The human lifespan
is about to expand 50 or 60 years,
and it's right around the corner.
Anyway, I haven't seen
evidence of that, but, yes,
if you want to put crazy amounts
of money into your health,
personal chef, IV drips on call,
hyperbaric chamber, red light therapy,
then, yes, most of the time,
you can squeeze out
a couple extra years.
- We're on the same page there.
- No, we're not.
You got to expand your mind, brother,
'cause I'm gonna be
the first man to climb
K2 at a hundred years old.
I'm gonna father a child at 115.
Well, I can see why that would be
critical work for you brother.
But I don't see the bigger picture.
Somebody's got to do it first.
And then, eventually,
everybody can do it.
Look at these numbers.
Just look and then tell me I'm crazy.
I am the bellwether
for humanity's future.
Ria?
Hey. Thank you so much for doing this.
SASHA: Yeah, of course.
You're Casey, right?
Yeah, yeah, uh, Casey Zink.
My name's Sasha Lubbock. I'm
a rheumatologist-immunologist
at the Holmes Clinic.
This is my colleague Ingrid Derian.
She specializes in neurology.
INGRID: Your symptoms are concerning
for elevated intracranial pressure.
We'll get you straight in for an MRI.
But I-I can't afford an MRI.
I keep saying that.
Our clinic works differently.
If you can't meet the costs,
your imaging is covered
by our operating grant.
"Liver of a 22-year-old."
(CHUCKLES) Well, you might want
to check and see if he wants it back.
Ha ha. You know what I mean.
Look I'd like you
to come aboard the team. Okay?
You can be the official
genetics consultant
for Anti-Aging Generation.
Anti-Aging Generation, meaning you.
AAG's a company.
It's a movement, too.
Believe what you like, but
this could mean
the world to your clinic.
And the funding I'm able to provide
is virtually unlimited.
Listen, congratulations on your liver.
Thank you.
But I'm not a concierge doctor.
CASEY (SCOFFS): An MRI?
I, uh, had five of these
in the same year.
INGRID: Five MRIs?
Were you dying?
I-I pitched for Penn State.
I got drafted by the Brewers
out of high school,
but I picked college ball.
And then I, um, I shredded my labrum
and lost my scholarship,
and, you know, I guess, here we are.
The only thing I really knew
how to do is throw a baseball,
and, um
now I can't even do that. (WINCES)
We're done here.
Perhaps we'll meet again,
young Ranger.
All right, bet.
Ranger. Now.
WATSON:
I hate to have to tell you this,
but you have a large growth
in your spinal cord.
It's called an ependymoma.
Is that, uh, is that a tumor?
Yes.
The safest
and most effective approach
is surgical removal.
But fortunately, we have
an excellent team here.
I'm gonna refer you
to Dr. Mary Morstan.
I was fine two months ago.
I'm healthy. What happened?
- I mean
- I'm sorry, Casey.
It's a lot to take in.
(KNOCK ON DOOR)
MARY: John.
I need to see you.
Excuse me one moment, please.
(MARY SIGHS)
I hate this as much as you do,
but I have had, I don't know,
12 calls from billing.
We need to do a breakdown
of care with your patient.
He's financially responsible.
Well, Casey is a patient
of the Holmes Clinic.
He's covered by our operating grant.
Your operating grant
is not operational.
Word came in a few hours ago.
The Holmes Clinic
is denying Casey's care.
- What?
- CASEY: I can't see.
SASHA: I'll get vitals.
I-I can't see. I can't see.
- What's happening?
- There's too much pressure on your optic nerve.
I need to do an
emergency lumbar puncture.
He could herniate. Administer
mannitol and steroids first.
Will I be able to see again?
If we move fast enough.
John, he's financially
responsible. He needs
- to consent to treatment.
- What? - What?
I have to pay? You said I was covered.
- You promised me.
- You will be covered, Casey. I'll take care of this.
That's our patient. Take care of him.
I will pay myself if I have to.
(BREATHING HEAVILY)
WATSON: Why are my patients
being denied care?
MYCROFT (WHISPERING):
They're not your patients
until they can be responsible
for their own treatment.
We don't worry about that here.
And why are you whispering?
I'm at my club.
We reject idle conversation.
This is the 21st century, Watson.
No one seeking treatment
is free from worry.
There's a 23-year-old
that's dying in this hospital.
23-year-olds are dying
all over the world.
It's rare, I'll grant you,
but there are eight billion people.
I'm treating Casey Zink.
Stop messing with my funding.
It's not your funding. It flows to you
courtesy of the Holmes family.
I am the only living Holmes, therefore
I offered you options, Watson.
I encouraged you
to resume aggressive research.
And all you had to do
was sign a couple of pieces of paper.
No, I do this
we do this to help people.
My research is never
gonna belong to your company.
Right.
So, that 23-year-old.
You said his name was Casey?
He'll just have to pay for
the treatment you're giving him.
- (TAPS KEY)
- (COMPUTER CHIMES)
♪
(TIRES SCREECH)
JOSEPH: I sleep ten
hours a night, Dr. Watson.
I don't wake up for just anyone.
Ranger said you had some questions.
Yes, so
when you said "unlimited funding,"
what does that mean?
It means exactly that.
It means you please me,
and I'll find a way to please you.
I have a patient that needs some help.
If you will pay for his treatment
all of his treatment
I'll work with you for a month,
and we can revisit after that.
One patient?
(LAUGHS)
I thought you'd cost more.
One patient for one month.
A month.
(LAUGHING): Sounds good.
Welcome to the team, Dr. Watson.
♪
INGRID: Do we have a sugar daddy now?
No, we do not have a sugar daddy.
I'm embarrassed
I even know what that means.
It just sounds like
you're getting in bed
with a rich guy
so that we can pay our bills,
and that's called
having a sugar daddy.
No, no, we're just working
through this situation
with Mycroft Holmes.
He didn't fund this clinic,
so he can't control
who we see forever.
In the meantime,
I've found alternative ways
to treat our patients.
Sugar daddy.
I'm not asking you
to provide concierge services
for Joseph Bell.
I'm gonna take that bullet.
All you have to do is prep
Casey Zink for surgery
and find out how a 23-year-old
came down with a spinal tumor.
Dr. Croft.
I'll go with you.
To Bell's. I'm interested in his work.
Because of course you are.
Okay, Joseph Bell is a lot
a whole lot
but longevity is
a legitimate field of study.
All right, fine. Come with me.
Ingrid, prep Casey for surgery
with Dr. Morstan
and bring back that tumor
for analysis.
Sasha and Stephens, get those
cancer cells under a microscope.
I'll be in Sewickley Heights,
taking one for the team.
Good luck with
your sugar daddy, Watson.
INGRID: Do you want to
go over the risks again?
Just, I'm 23.
I shouldn't have a tumor.
It's not fair.
No one's saying it is.
But why am I even here?
All those people in that free clinic,
they all need help, so why is it me?
Why am I getting the red carpet?
No, you don't
you don't have to answer.
I haven't walked off the ledge yet.
The ledge.
One day
you wake up, and you've
been sick long enough,
and you've been broke long enough,
and then, suddenly, people
won't look at you anymore.
And they can't look at you
because the questions
you make them ask
are just too big to answer.
I probably got three years
before that.
'Cause you can still look at me,
you can picture someone
who doesn't live in their car.
And that's that's why I'm here.
That's not fair, either.
But you are here,
and there's a surgeon waiting.
JOSEPH: Gear up, boys.
Need you in the logo for socials.
I'm already dressed, but thank you.
All right, well, at least hold
a water bottle or something.
And wh-what's your handle?
I want to tag you in the post.
- I don't have a handle.
- (ALARM CHIMING)
Oh.
(AIR HISSING)
(EXHALES)
You're gonna need a handle, buddy.
And I was thinking you could,
uh, hold up your book.
You know about my book?
Eat Right for Your Genotype.
Yeah, my chef and I
reviewed it together.
All right, so we're announcing you
as the newest member of the team.
But first, do your thing.
Read me.
Read you?
We do our own genetic tests.
That's gonna take some time.
I'm not talking about the DNA tests.
I'm talking about the magic trick.
Read my face.
Tell me my genetic destiny.
It's not that simple.
Well, give me something.
Okay.
Increased nasal height
due to inherited material
in your ATF3 genome region,
prominent brow, mild occipital bun.
I'd say you're about
four percent Neanderthal.
No!
(CHUCKLING):
Not the Neanderthal thing again.
Well, it's actually
very useful information.
You're susceptible to type 2 diabetes
- and Crohn's disease.
- I'm not saying you're wrong.
I'm just saying that
that word, "Neanderthal,"
cannot be associated with me
or with AAG.
Yes, but "Neanderthal" is
actually a misunderstood term.
It doesn't matter if it's true, man.
It matters what people think.
So don't mention my name
in connection with that word.
(CHUCKLES) It's all good.
Let's get this post up.
RANGER: "AAG" on three.
One, two, three.
ALL: AAG.
SASHA: "Had a blast
"talking genetics with
John Watson and Adams Croft,
the newest doctors on the AAG team."
Who is Adams Croft?
Joseph Bell must have gotten
the two of you mixed up.
Added an "S" to Adam's name.
- He's gonna be so pissed.
- Why? It's a typo.
Well, it's a typo,
but it's also right.
Adam's real name it's Adams.
(LAUGHING)
Somewhere along the way,
my brother decided to pretend
he's not a New England
prep school kid.
- Thus was born Adam Croft.
- Mm.
Stephens and Adams.
- Extra S's for everybody.
- Don't say anything.
He's sensitive.
Actually, can you take a shift?
- I'm going cross-eyed. (LAUGHS)
- Mm-hmm.
Oh, I got a text from Ria.
She wants us all to get together
for drinks tomorrow.
I have training after work.
The hospice. Remember?
So you're going ahead with that?
It'll be good for me.
- Get out of my own head.
- Look at you.
Volunteer work,
sitting in the morning sun,
cold plunges?
You're really going after it,
treating whatever's going on with you.
You mean major depressive disorder?
Well, according to Ingrid.
I respect Ingrid.
We all respect Ingrid,
but can we agree that she's maybe not
the world's leading expert
in mental health?
♪
I think it's great what you're doing,
but we are, you know, doctors.
If you're gonna treat a diagnosis,
shouldn't you have
an actual diagnosis?
I can get you names
qualified psychiatrists
and maybe you could even talk
to one of them.
Right. Therapy.
Yeah, maybe.
- (SIGHS)
- Hmm.
- That's strange.
- What?
Casey's cancer cells.
They should have died by now,
but look.
SASHA: They're replicating.
MARY: Barrier incision complete.
Almost there.
Margin's clear laterally.
Mobilizing the inferior aspect
of the tumor.
SURGICAL ASSISTANT:
Tumor is soft. Plane's holding.
- MARY: Suction.
- (WHOOSHING)
Opinion, Dr. Derian?
INGRID: Is it a feeder vessel?
MARY: Plane's not clear.
- More suction.
- (WHOOSHING)
We're into normal cord.
I'm backing off.
Having a hard time in here.
Dr. Derian, what are you seeing?
INGRID: The tumor's
dorsal edge looks fused.
MARY: Agree.
I can't risk permanent damage.
I'm not gonna chase it.
We're calling it.
INGRID:
Subtotal resection should still
relieve Casey of his symptoms.
MARY: But he'll need more treatment.
Not the win I was hoping for.
(INGRID SIGHS)
We debated whether to call you here.
I was just reviewing
Joseph Bell's stool log.
You can call me anytime.
We've been following Adams' socials.
Seems like Bell's a handful.
Eh, too much money,
too many supplements.
Anyway, let's talk about
our real patient.
- Is Casey awake?
- Still in recovery.
He doesn't know his surgery failed.
But that's not even
his biggest problem.
We've been analyzing the cells
from the tumor biopsy.
We just finished the RNA sequencing.
WATSON: Is this the right sample?
SASHA: We quadruple-checked.
Look at the end of the RNA sequence.
- Should have a poly(A) tail.
- A short string of A's.
WATSON: There are some G's, too.
SASHA: Not to mention it's long.
Too long.
A tail like this
couldn't occur naturally.
Which suggests genetic modification.
Somebody messed with Casey's genes.
This is genetic tinkering.
Casey's cancer was man-made.
He's sick because
someone made him sick.
I had a mate who died
like that cancer.
Ol' Tom Dinkle.
Smoker from the age of ten.
But that's not what you mean
when you say "man-made," is it?
No, cancer can come
from genetic predisposition,
exposure to carcinogens,
a lifetime of bad habits.
This this is different.
If I sequence a typical cancer cell,
its genetics would be random,
a shuffled card deck.
Casey's cancer isn't shuffled.
It's uniform. It's engineered.
Meaning?
Meaning his disease is the result
of a deliberate genetic modification.
What's fascinating
and, frankly, nightmarish
is that these cells seem to be
I don't know, unkillable?
We treated these cells
with a full round of chemo.
Zero effect.
Like the bad guy from a horror movie.
CASEY: So I still have cancer,
I can't move any of my limbs,
and you're saying
someone did this to me?
Well, I can't speak
to the larger issues,
but as for the paralysis,
you're still in the window
of post-surgery swelling.
Is this Erin Brockovich stuff?
Did I live under
the wrong power lines,
sip the wrong water?
No, this is something else:
gene editing.
Somebody hacked your genome
and gave you a form of cancer
that, as far as we can tell,
is impervious to existing treatment.
What?
How?
That's what we're hoping
you can help us with.
If you haven't voluntarily submitted
to a procedure
that would alter your genes
I mean, did I volunteer
to get immortal cancer?
No, of course I didn't.
Then someone did this
without you knowing about it.
Have you had any injections
recently, a blood draw?
Any medical procedure
could give us a handhold.
I-I don't even know where
to start with all that.
I'm basically a human guinea pig.
Uh, what does that mean?
After I lost my scholarship,
I had two different
call center jobs
that got sent overseas.
Data entry that lasts
as long as it lasts,
server gigs that go away
when the restaurant closes.
And in between all that,
I sign up for studies.
Medical trials.
Sleep stuff, consumer products,
anything that pays the bills.
How many studies?
I don't know.
A few a year for a few years.
Any of these studies
involve gene editing?
Not that they said.
Not that I remember.
But I don't always read
the terms and conditions.
ADAM: Remind me never to
sign another release form again.
SASHA: You can't just slip
"man-made cancer" into the fine print.
I mean, I don't read those things.
- Does anyone?
- (PHONE VIBRATING)
Casey's tested food dyes,
hair products.
He did a sleep deprivation study
at Pitt.
Man, this is bleak.
Not all of us have rich parents.
Nice jacket, by the way.
They're comfortable.
I got one for everyone.
I don't wear my boss's merch,
but thanks.
Come on, leave Adams alone.
Let's just focus on the studies.
- Adams?
- (PHONE VIBRATING)
WATSON: Any trial at a university
or a big company would be regulated.
But Casey said that he participated
in some privately funded studies.
- Let's start there.
- How?
Where would he keep his records?
He has a car, right?
He said it's parked
in his friend's driveway.
He had her move it when he came
here so it wouldn't get towed.
- Okay, go there.
- (PHONE VIBRATING)
See what you can find. Crofts?
Sit with Casey. When he wakes up,
see if you can get a more
- detailed history.
- (PHONE VIBRATING)
Is that our Neanderthal sugar daddy?
I'm pretty sure we're
contractually forbidden
from saying that word.
Is that our secretly Neanderthal
sugar daddy?
WATSON: I wish.
It's our other sugar daddy.
MYCROFT (OVER COMPUTER):
Punctuality, Dr. Watson.
These meetings will be better
for both of us
if we keep to a schedule.
Yeah, we don't need
to check in every day.
In fact, we don't need
to check in at all.
Your brother endowed this clinic
to give me the freedom
to run things my way.
He did that
with money from my company.
We both know that you founded
this company based on his ideas.
His idea would have died
on the vine if not for me.
You obviously have issues
with your brother.
I don't see why my patients
should be in the middle of that.
Had issues, Watson.
One can hardly have issues
with a dead man.
This doesn't have to be adversarial.
I'm not here to close your doors.
No, but you're trying to get
some kind of revenge on your brother,
and I'm never gonna
go along with that.
We were never
particularly close, you know.
I always fancied him a loner,
and then you came along.
You disproved my whole theory.
He just had no interest in me.
So, we will have our daily meeting
and our mutually beneficial
partnership,
even if there are growing pains
along the way.
(CAR DOOR LOCK BEEPS)
(CLICKS TONGUE, SIGHS)
SASHA: Casey tried
to make it like home.
He probably thought his back pain
came from sleeping in the car.
Take the back seat. I got the trunk.
SASHA: Can I ask you something?
A favor, I guess.
I'm listening.
Stephens believes you.
He may have depression.
I'm not a psychiatrist.
He asked me what I thought.
I told him.
That's the thing.
He thinks you're right.
But he won't go see someone
who could actually diagnose him.
- That doesn't make sense.
- Correct.
He'll sit in the morning light.
He signed up to sit
with hospice patients.
But every time I bring up
therapy, he changes the subject.
I'm his girlfriend.
I don't want to be his mom.
And I thought maybe you could
give it the old college try.
Oh, so I get to be his mom?
It's different with you two.
Y'all have something now.
Oh, we have something?
I'm not jealous.
I was just wondering
if you'll talk to him.
Hey, come look at this.
Uh, pay stubs, signed agreements.
Casey kept records.
Have you heard of this place?
Primal BioTech?
- What's that?
- STEPHENS: This is weird.
Primal BioTech website
is full of broken links.
It's pretty much defunct,
as far as I can tell.
Their nondisclosure agreement
is state-of-the-art.
I emailed Lauren.
She says it's unusually dense.
It's way beyond
the standard boilerplate.
Kind of like someone had
something to hide.
What is this place?
Casey remembers two visits
to the same temp office.
First was a blood draw.
Then, three weeks later, an IV drip.
A lab tech said it was
a vitamin supplement
tailored to his genome.
A global search of Casey's email
shows that Primal BioTech
sent 57 follow-up questionnaires
over a span of two months.
The email replies
just bounce back now.
This is a shell company.
They conducted one study
and then vanished
- without a trace.
- WATSON: He did leave a trace.
It was there the whole time.
It takes real arrogance
to sign your work.
What are you talking about, Watson?
I'm talking about Casey's genome.
Take a look and see what's coded
on the RNA tail sequence.
"AAG." Anti-Aging Generation.
The company that got Casey sick
is owned by Joseph Bell.
So, one man comes to us for treatment,
desperate for
whatever help he can get,
another hires us on
but just as the latest
in an endless list
of luxury purchases,
and you're saying, guv,
that they're connected?
That Casey's sick
because of Joseph Bell?
Remember what Sherlock said:
"The universe is rarely so lazy."
The clinic it's the spoke
in a giant wheel
made of medical science
and cutting-edge innovation.
Now, of course,
both of them wound up here.
I mean, it was the only place
they could wind up.
Sasha, tell us what happened.
Casey signed up for a study.
Joseph's people injected him
with whatever,
an editing agent
that turned on a specific gene,
one meant to boost longevity and
squeeze out a few more years.
They didn't set out
to give him cancer.
That's just how it turned out.
What happens now?
I assume Casey can sue Joseph
if he wants to.
If he can find a lawyer
who can crack
those terms and conditions.
Oh, no contract in the world
can cover death by accidental cancer.
Yeah, but does it matter?
Casey's dying.
Money can't help with that.
Whatever it was
that Joseph gave Casey,
we need it.
We need to find it
and we need to study it.
If this cancer can be caused
by genetic manipulation,
then we can work with that.
If Bell even still has the stuff.
Joseph Bell wants to live forever.
If he can't have that,
he'll settle for 20 extra years.
Somewhere inside that compound,
we will find what we're looking for.
So we just walk inside Bell's estate,
poke around without drawing suspicion?
No. He's gonna invite us inside.
As soon as I put up
this post, message
I'm sorry, what am I supposed
to call one of these things?
You're signing up to social media?
Yeah, just for now.
So interesting to learn
that @TheJosephBellAAG
is part Neanderthal.
These titans of the tundra
are the ultimate survivors.
MARY: Go, Neanderthals.
@TheJosephBellAAG repping
the smooth-brained titans
of the tundra.
INGRID: Hey, guys. Neanderthals rock.
@TheJosephBellAAG,
let's go on a quest for fire.
(INDISTINCT OVERLAPPING VOICES)
That's an A-plus
on the thumbs-up test.
(CHUCKLES) That's a good sign, right?
It's a great sign.
It means your swelling is down.
For now, rest, we'll continue
to monitor your progress,
but I'm optimistic
you will regain full function.
So lasting paralysis is off the table?
It is.
I'm really happy for you, Casey.
Just in time to die, though, right?
We're working on a treatment, Casey.
We haven't given up.
Yeah, well, what if this
doesn't work out?
Right, how much do I have
coming to me?
I mean, if this study kills me at 23,
at least I'll be rich, right?
You can't be rich and also dead.
I mean, come on. Can I at least pick?
I wish it worked out that way.
I really do.
(TAKES DEEP BREATH)
What the hey, boys?
Half the Internet's
calling me a caveman.
"Caveman-" that's actually
not accurate.
Well, like I said,
accurate don't matter
when the whole world is clowning you.
You're right. It's my bad.
I get lost in my head sometimes.
I'll delete the post.
No, it's already been re-shared
60,000 times.
Hmm.
How about we give the world
something else to talk about?
Telomere lengthening.
That's where we tweak the ends
of your chromosomes.
Now, if you want to add
some extra years
to your lifespan, that's the real.
I'm down.
Now, you're sure?
'Cause this is gene editing work.
Am I sure?
(GIGGLES) Yeah.
I'm not just vitamins
and cold plunges.
I'm trying to get revolutionary.
Safe and legal just means
slow and boring,
so LFG, buddy.
Jack me up if you dare.
Joseph, after your blood draw,
we should replenish your fluids
with an IV.
I brought a baseline solution,
but I assume you have your own.
Yeah, I don't put anything
baseline in my body.
Not when I have a medical supply room
tailored to my exact genome.
I mean, why should you?
I mean, it's a good point.
(LAUGHING): Exactly. Exactly, John.
- Yeah, yeah.
- JOSEPH: Thank you. I agree.
Hey, Ranger, why don't you show
Dr. Croft the inner sanctum?
RANGER: Mr. Bell
calls this the longevity bunker.
"Mr. Bell"? You can't call him Joseph?
I'm pretty sure he likes "Mr. Bell."
(KEYPAD BEEPING)
Okay.
♪
(SHINWELL SPEAKS INDISTINCTLY)
(RANGER SPEAKS INDISTINCTLY)
SHINWELL: I don't know.
Life's a bit short to be looking
after someone you don't like.
Nursing school.
Tell me about that. What's that like?
SHINWELL: You've done your research.
Well, this kind of work,
it has a ceiling, right?
You've turned it into something else.
- SHINWELL: Hmm.
- RANGER: You know,
I was a medic in my unit.
I'd say that puts you
ahead of the game.
- RANGER: Oh, yeah?
- Yeah.
RANGER: Figured as much.
SHINWELL: Swing down
to the clinic sometime
- without him.
- Absolutely, I'll do that.
And there we are.
The poison apple.
Casey's illness began
when the contents
of this vial got into his system.
If we do our jobs right,
this is what can save him.
You want to make a small
interfering RNA treatment
from one sample?
We can do it.
We can make an off switch
designed specifically
to target Casey's cancer.
I get it, siRNA is
the future of medicine,
but this hasn't been widely tested.
There are a million variables.
You're wondering what we do
if it doesn't work.
- I'm asking a question.
- Well, if it doesn't work,
then he dies, obviously.
That's happening anyway.
Casey's cancer comes from
a single gene manipulation.
This is the perfect test case
for the treatment.
Can anyone tell me why?
SiRNA gets inside the cancer cells,
sends them a message to self-destruct.
It's kind of poetic
if you think about it.
How do you kill an immortal cancer?
- You make it kill itself.
- (DOOR OPENS)
STEPHENS: Watson.
I ran the samples you took
from Joseph Bell.
They tested them against
the markers you requested.
And?
JOSEPH:
I think you have this backwards.
I'm not really on call
to show up wherever you want.
Shh. Quiet, please.
My patient's asleep.
This is Casey Zink.
You don't know him,
but he has a tumor in his spine.
That's terrible. He's so young.
He signed up for a trial with
a company called Primal BioTech.
They put something in his IV.
It was a genome tweak meant
to extend the human lifespan.
Instead, he got cancer.
You did it, Joseph. You did it.
I mean, you created something
that just won't die.
Unfortunately, it's not you.
It's this cancer.
(CHUCKLES) What is this?
I've never heard the name Casey Zink
- in my entire life.
- Yeah, of course not.
There's probably five layers
between you and Casey.
But he's the one that
your shell company ran tests on.
He's dying because of what you did.
(SCOFFS)
- You're fired.
- You might not want to leave.
I have some more news for you,
brother.
Now, you, your company or whoever,
you sent Casey some follow-up surveys.
He reported no side effects.
You don't strike me as a patient man.
So when he said he was fine,
I'm guessing that
you gave yourself
exactly what you gave him
and probably more than one dose.
Am I right?
Nothing you're saying is accurate.
I acknowledge nothing.
I admit nothing.
Dr. Watson?
- Good morning, Casey.
- Morning.
This is Joseph Bell.
He created a company
called Primal BioTech.
He's the one that made you sick.
- JOSEPH: No.
- What?
That's not true. It's not true.
And, see, here's the thing
he is also sick himself.
Joseph infused himself
with the same thing he gave you.
And we checked his markers.
He doesn't know it yet,
but he's very, very ill.
Joseph has cancer, too.
No. (CHUCKLES) No.
I'm Joseph Bell.
I have the liver of a 22-year-old.
You've got cancer, Joseph.
A very unique
and difficult-to-treat form of cancer.
No. No.
It's in your spine.
I understand this is a lot to take in,
and I encourage you to get
a second opinion if you'd like.
I have my blood read
every single morning.
Yeah, but they're not
looking for these
very specific tumor markers.
We did.
We have a treatment.
If you're interested,
I'd say right now
my clinic is the only place
in the world that can help you.
You said the cells can't be killed.
They can be convinced
to kill themselves.
We developed an siRNA treatment.
Casey's already getting it.
If you want,
we can do the same for you.
I'm your doctor,
just like I'm Casey's doctor.
Yeah, of course I want it.
If I'm really sick,
of course I want it.
Why would you even ask me that?
What are you gonna do for Casey Zink?
I'm already paying for his treatment.
What else do you want from me?
He has you dead to rights.
You created Primal BioTech.
You gave him cancer.
So you say.
So I know.
I'm the only person
in the entire world
that could be your doctor.
There's a sick kid in this room
who has cancer because of you.
As far as I'm concerned,
whatever he wants from you, you do it.
(CHUCKLES)
Or else?
I can only take so many patients.
It takes time, you know,
to find the right person.
At first, they sent me
to therapists, psychiatrists.
Then I found a few on my own.
Most are very easy to manipulate.
Now I have one who helps.
And it does help.
I'm never doing talk therapy.
Okay.
Why, though?
You're a scientist. There's data.
Stephens Croft the Fourth
didn't do much
with everything life handed to him.
You're a Fifth?
Stephens Four was
a very good club tennis player
and not much else.
He smiled a lot.
And he was depressed as hell.
After the divorce, he went to maybe
four psychiatrists that I knew about.
The last one got really close to him.
Conversations day and night.
It was weird,
but he said it was helping.
Then he crashed his car on Cape Cod.
Died in the helicopter
on the way to the hospital.
And those things are connected?
Maybe not, maybe yes.
It was an accident.
Unless it wasn't.
What do you think?
I've never said this to Adam.
Not to Sasha, not to anyone.
I don't think that wreck
was an accident.
I think my dad did it on purpose.
I'm never going to therapy.
Stephens.
I'm sorry about what happened
to your dad.
Okay, whatever it was, I'm sorry.
You've never said this to anyone.
Why say it to me?
Because you understand.
(DOOR OPENS, CLOSES)
Thank you so much for coming.
No problem.
Uh
I have to be honest, though,
I am a little nervous.
You'll be fine.
Just sit with her. Watch her shows.
(TV PLAYING INDISTINCTLY)
You okay?
I have a hair appointment.
It's been a while.
Of course.
Do what you need to.
We'll make it.
(CHUCKLES SOFTLY)
You have my number if you need me.
Mm-hmm.
(PICKS UP KEYS)
(DOOR OPENS)
(DOOR CLOSES)
RUTH: Who are you?
Um
My name is Stephens Croft.
I'm here in case you need anything.
I'm here to spend time with you.
That's good.
I'm glad.
Still doing rounds today, sir?
"Sir" ain't necessary.
And I don't do rounds.
I shadow people doing rounds.
Okay, you're still shadowing
people doing rounds?
I am indeed.
Tell you what.
You hang a few feet back,
you observe all you like.
Thank you, sir.
(HANDS CLASP)
Thank you, Shinwell.
That's a weird name.
Yeah yeah yeah yeah,
yeah yeah yeah yeah ♪
Yeah yeah yeah yeah,
yeah yeah yeah ♪
Yeah yeah yeah yeah,
yeah yeah yeah yeah ♪
- (KNOCK AT DOOR)
- (DOOR OPENS)
("THE YEAH YEAH YEAH SONG"
BY THE FLAMING LIPS PLAYING)
WATSON: Doing great, Casey.
Your cells are really responding
to the treatment.
I got lawyers coming by later.
It's like
you know, everyone wants
to know me all of a sudden.
Yeah, that's because
you're money in the bank.
You're gonna make it,
and you're gonna get
everything you want.
You should start thinking about
what you're gonna do with it.
Who are you gonna be now, Casey?
These numbers they're not good.
I know.
Your cancer is mutating too fast
for the treatment to take hold.
My lawyers are giving that kid
everything he asked for.
We're playing ball.
It's not like paying a fine.
This isn't something you can control.
Look, I'm sorry.
We're gonna keep trying,
but you really should be
in the hospital.
With all your power ♪
With all your power ♪
With all your power ♪
What would you do? ♪
With all your power ♪
With all your power ♪
With all your power ♪
What would you do? ♪
- (CAR LOCK BEEPING)
- With all your power ♪
(ENGINE REVVING)
It's okay.
With all your power ♪
With all your power ♪
(FLATLINE BEEP)
What would you do? ♪
(SONG ENDS)
Hello?
Mycroft.
That's my desk.
Did you pay for it?
Get up, or it won't be lawyers
solving our problems.
I can give you what you want.
I can make myself scarce.
I can leave you to run this
clinic under your own auspices.
Very good. Thank you. Goodbye.
You haven't heard me out.
You need to give me
something in return.
My company is reeling.
The formula that my brother left,
it doesn't work the way that
he said it would in the will.
Sherlock did this, Dr. Watson.
He left a poison pill behind
to wreck everything I built
in both our names.
I don't know anything about that.
I think you do.
Sherlock's alive.
He has to be.
He's watching somewhere,
he's laughing.
Tell me I'm right.
Tell me my brother's still alive.
Tell me where he is.
Tell me what I need to know,
and I will withdraw
from your business directly.
I'll leave you alone.
Where is Sherlock Holmes?
("FLASH OF THE BLADE"
BY IRON MAIDEN PLAYING)
sync & corrections awaqeded
- (BREATHING DEEPLY)
- RIA (MUFFLED): Casey.
(PULSE BEATING)
Casey?
(CLEARLY): Casey?
You're here again. What's wrong?
Yeah, it's just, it's my back.
It-It's getting worse, and
and now I got these-these headaches,
this throbbing in my ears,
and nothing's drowning it out.
Hey, you need a hospital.
I need a hospital.
I need insurance.
I need a lot of things.
Okay, wait here, Casey.
I'll find a doctor.
This morning's numbers, Mr. Bell.
Ranger, my name is Joseph.
I keep telling you that.
These numbers are good.
I've got the liver of a 22-year-old,
kidneys tracking at 25.
We should make a post for socials.
Tell Kristen to write up a script.
CLERK: Number 92, please.
The doctor's ready to see you.
Number 92.
Do you want me to confirm
your interview at 1100?
I doubt the doctor
would call it an interview.
I hear the man's got an ego.
But confirm.
And get the car ready and come back.
- Yes, sir.
- RIA: I'm so sorry, we're short-staffed,
Casey. Listen,
you could be having a stroke,
an aneurysm, a hemorrhage.
The point is, I don't know.
I'm just a volunteer.
They can't turn you away from an ER.
You need tests,
imaging, an MRI probably.
There's what I need and
there's what I can afford, man.
I know about a place.
A girl I used to see at Pitt
she works there.
Insurance, your ability to pay
it's not always their first concern.
What-What's the place?
- (INDISTINCT ARGUMENT)
- One second, all right?
Car's ready, sir.
Remind me what
I'm putting into the GPS.
BOTH: It's called the Holmes Clinic.
Okay. Thank you.
What kind of name is Ranger?
My father wanted me
to be an Army Ranger.
A Ranger named Ranger.
So, did you make the cut?
Three tours. And you?
Where'd you get your training?
The High Down
Youth Offender Institution.
More of an informal program, really.
JOSEPH: Aging is a disease.
Do you agree, Dr. Watson?
I agree that it sounds catchy.
It's more than that.
This is critical work.
The human lifespan
is about to expand 50 or 60 years,
and it's right around the corner.
Anyway, I haven't seen
evidence of that, but, yes,
if you want to put crazy amounts
of money into your health,
personal chef, IV drips on call,
hyperbaric chamber, red light therapy,
then, yes, most of the time,
you can squeeze out
a couple extra years.
- We're on the same page there.
- No, we're not.
You got to expand your mind, brother,
'cause I'm gonna be
the first man to climb
K2 at a hundred years old.
I'm gonna father a child at 115.
Well, I can see why that would be
critical work for you brother.
But I don't see the bigger picture.
Somebody's got to do it first.
And then, eventually,
everybody can do it.
Look at these numbers.
Just look and then tell me I'm crazy.
I am the bellwether
for humanity's future.
Ria?
Hey. Thank you so much for doing this.
SASHA: Yeah, of course.
You're Casey, right?
Yeah, yeah, uh, Casey Zink.
My name's Sasha Lubbock. I'm
a rheumatologist-immunologist
at the Holmes Clinic.
This is my colleague Ingrid Derian.
She specializes in neurology.
INGRID: Your symptoms are concerning
for elevated intracranial pressure.
We'll get you straight in for an MRI.
But I-I can't afford an MRI.
I keep saying that.
Our clinic works differently.
If you can't meet the costs,
your imaging is covered
by our operating grant.
"Liver of a 22-year-old."
(CHUCKLES) Well, you might want
to check and see if he wants it back.
Ha ha. You know what I mean.
Look I'd like you
to come aboard the team. Okay?
You can be the official
genetics consultant
for Anti-Aging Generation.
Anti-Aging Generation, meaning you.
AAG's a company.
It's a movement, too.
Believe what you like, but
this could mean
the world to your clinic.
And the funding I'm able to provide
is virtually unlimited.
Listen, congratulations on your liver.
Thank you.
But I'm not a concierge doctor.
CASEY (SCOFFS): An MRI?
I, uh, had five of these
in the same year.
INGRID: Five MRIs?
Were you dying?
I-I pitched for Penn State.
I got drafted by the Brewers
out of high school,
but I picked college ball.
And then I, um, I shredded my labrum
and lost my scholarship,
and, you know, I guess, here we are.
The only thing I really knew
how to do is throw a baseball,
and, um
now I can't even do that. (WINCES)
We're done here.
Perhaps we'll meet again,
young Ranger.
All right, bet.
Ranger. Now.
WATSON:
I hate to have to tell you this,
but you have a large growth
in your spinal cord.
It's called an ependymoma.
Is that, uh, is that a tumor?
Yes.
The safest
and most effective approach
is surgical removal.
But fortunately, we have
an excellent team here.
I'm gonna refer you
to Dr. Mary Morstan.
I was fine two months ago.
I'm healthy. What happened?
- I mean
- I'm sorry, Casey.
It's a lot to take in.
(KNOCK ON DOOR)
MARY: John.
I need to see you.
Excuse me one moment, please.
(MARY SIGHS)
I hate this as much as you do,
but I have had, I don't know,
12 calls from billing.
We need to do a breakdown
of care with your patient.
He's financially responsible.
Well, Casey is a patient
of the Holmes Clinic.
He's covered by our operating grant.
Your operating grant
is not operational.
Word came in a few hours ago.
The Holmes Clinic
is denying Casey's care.
- What?
- CASEY: I can't see.
SASHA: I'll get vitals.
I-I can't see. I can't see.
- What's happening?
- There's too much pressure on your optic nerve.
I need to do an
emergency lumbar puncture.
He could herniate. Administer
mannitol and steroids first.
Will I be able to see again?
If we move fast enough.
John, he's financially
responsible. He needs
- to consent to treatment.
- What? - What?
I have to pay? You said I was covered.
- You promised me.
- You will be covered, Casey. I'll take care of this.
That's our patient. Take care of him.
I will pay myself if I have to.
(BREATHING HEAVILY)
WATSON: Why are my patients
being denied care?
MYCROFT (WHISPERING):
They're not your patients
until they can be responsible
for their own treatment.
We don't worry about that here.
And why are you whispering?
I'm at my club.
We reject idle conversation.
This is the 21st century, Watson.
No one seeking treatment
is free from worry.
There's a 23-year-old
that's dying in this hospital.
23-year-olds are dying
all over the world.
It's rare, I'll grant you,
but there are eight billion people.
I'm treating Casey Zink.
Stop messing with my funding.
It's not your funding. It flows to you
courtesy of the Holmes family.
I am the only living Holmes, therefore
I offered you options, Watson.
I encouraged you
to resume aggressive research.
And all you had to do
was sign a couple of pieces of paper.
No, I do this
we do this to help people.
My research is never
gonna belong to your company.
Right.
So, that 23-year-old.
You said his name was Casey?
He'll just have to pay for
the treatment you're giving him.
- (TAPS KEY)
- (COMPUTER CHIMES)
♪
(TIRES SCREECH)
JOSEPH: I sleep ten
hours a night, Dr. Watson.
I don't wake up for just anyone.
Ranger said you had some questions.
Yes, so
when you said "unlimited funding,"
what does that mean?
It means exactly that.
It means you please me,
and I'll find a way to please you.
I have a patient that needs some help.
If you will pay for his treatment
all of his treatment
I'll work with you for a month,
and we can revisit after that.
One patient?
(LAUGHS)
I thought you'd cost more.
One patient for one month.
A month.
(LAUGHING): Sounds good.
Welcome to the team, Dr. Watson.
♪
INGRID: Do we have a sugar daddy now?
No, we do not have a sugar daddy.
I'm embarrassed
I even know what that means.
It just sounds like
you're getting in bed
with a rich guy
so that we can pay our bills,
and that's called
having a sugar daddy.
No, no, we're just working
through this situation
with Mycroft Holmes.
He didn't fund this clinic,
so he can't control
who we see forever.
In the meantime,
I've found alternative ways
to treat our patients.
Sugar daddy.
I'm not asking you
to provide concierge services
for Joseph Bell.
I'm gonna take that bullet.
All you have to do is prep
Casey Zink for surgery
and find out how a 23-year-old
came down with a spinal tumor.
Dr. Croft.
I'll go with you.
To Bell's. I'm interested in his work.
Because of course you are.
Okay, Joseph Bell is a lot
a whole lot
but longevity is
a legitimate field of study.
All right, fine. Come with me.
Ingrid, prep Casey for surgery
with Dr. Morstan
and bring back that tumor
for analysis.
Sasha and Stephens, get those
cancer cells under a microscope.
I'll be in Sewickley Heights,
taking one for the team.
Good luck with
your sugar daddy, Watson.
INGRID: Do you want to
go over the risks again?
Just, I'm 23.
I shouldn't have a tumor.
It's not fair.
No one's saying it is.
But why am I even here?
All those people in that free clinic,
they all need help, so why is it me?
Why am I getting the red carpet?
No, you don't
you don't have to answer.
I haven't walked off the ledge yet.
The ledge.
One day
you wake up, and you've
been sick long enough,
and you've been broke long enough,
and then, suddenly, people
won't look at you anymore.
And they can't look at you
because the questions
you make them ask
are just too big to answer.
I probably got three years
before that.
'Cause you can still look at me,
you can picture someone
who doesn't live in their car.
And that's that's why I'm here.
That's not fair, either.
But you are here,
and there's a surgeon waiting.
JOSEPH: Gear up, boys.
Need you in the logo for socials.
I'm already dressed, but thank you.
All right, well, at least hold
a water bottle or something.
And wh-what's your handle?
I want to tag you in the post.
- I don't have a handle.
- (ALARM CHIMING)
Oh.
(AIR HISSING)
(EXHALES)
You're gonna need a handle, buddy.
And I was thinking you could,
uh, hold up your book.
You know about my book?
Eat Right for Your Genotype.
Yeah, my chef and I
reviewed it together.
All right, so we're announcing you
as the newest member of the team.
But first, do your thing.
Read me.
Read you?
We do our own genetic tests.
That's gonna take some time.
I'm not talking about the DNA tests.
I'm talking about the magic trick.
Read my face.
Tell me my genetic destiny.
It's not that simple.
Well, give me something.
Okay.
Increased nasal height
due to inherited material
in your ATF3 genome region,
prominent brow, mild occipital bun.
I'd say you're about
four percent Neanderthal.
No!
(CHUCKLING):
Not the Neanderthal thing again.
Well, it's actually
very useful information.
You're susceptible to type 2 diabetes
- and Crohn's disease.
- I'm not saying you're wrong.
I'm just saying that
that word, "Neanderthal,"
cannot be associated with me
or with AAG.
Yes, but "Neanderthal" is
actually a misunderstood term.
It doesn't matter if it's true, man.
It matters what people think.
So don't mention my name
in connection with that word.
(CHUCKLES) It's all good.
Let's get this post up.
RANGER: "AAG" on three.
One, two, three.
ALL: AAG.
SASHA: "Had a blast
"talking genetics with
John Watson and Adams Croft,
the newest doctors on the AAG team."
Who is Adams Croft?
Joseph Bell must have gotten
the two of you mixed up.
Added an "S" to Adam's name.
- He's gonna be so pissed.
- Why? It's a typo.
Well, it's a typo,
but it's also right.
Adam's real name it's Adams.
(LAUGHING)
Somewhere along the way,
my brother decided to pretend
he's not a New England
prep school kid.
- Thus was born Adam Croft.
- Mm.
Stephens and Adams.
- Extra S's for everybody.
- Don't say anything.
He's sensitive.
Actually, can you take a shift?
- I'm going cross-eyed. (LAUGHS)
- Mm-hmm.
Oh, I got a text from Ria.
She wants us all to get together
for drinks tomorrow.
I have training after work.
The hospice. Remember?
So you're going ahead with that?
It'll be good for me.
- Get out of my own head.
- Look at you.
Volunteer work,
sitting in the morning sun,
cold plunges?
You're really going after it,
treating whatever's going on with you.
You mean major depressive disorder?
Well, according to Ingrid.
I respect Ingrid.
We all respect Ingrid,
but can we agree that she's maybe not
the world's leading expert
in mental health?
♪
I think it's great what you're doing,
but we are, you know, doctors.
If you're gonna treat a diagnosis,
shouldn't you have
an actual diagnosis?
I can get you names
qualified psychiatrists
and maybe you could even talk
to one of them.
Right. Therapy.
Yeah, maybe.
- (SIGHS)
- Hmm.
- That's strange.
- What?
Casey's cancer cells.
They should have died by now,
but look.
SASHA: They're replicating.
MARY: Barrier incision complete.
Almost there.
Margin's clear laterally.
Mobilizing the inferior aspect
of the tumor.
SURGICAL ASSISTANT:
Tumor is soft. Plane's holding.
- MARY: Suction.
- (WHOOSHING)
Opinion, Dr. Derian?
INGRID: Is it a feeder vessel?
MARY: Plane's not clear.
- More suction.
- (WHOOSHING)
We're into normal cord.
I'm backing off.
Having a hard time in here.
Dr. Derian, what are you seeing?
INGRID: The tumor's
dorsal edge looks fused.
MARY: Agree.
I can't risk permanent damage.
I'm not gonna chase it.
We're calling it.
INGRID:
Subtotal resection should still
relieve Casey of his symptoms.
MARY: But he'll need more treatment.
Not the win I was hoping for.
(INGRID SIGHS)
We debated whether to call you here.
I was just reviewing
Joseph Bell's stool log.
You can call me anytime.
We've been following Adams' socials.
Seems like Bell's a handful.
Eh, too much money,
too many supplements.
Anyway, let's talk about
our real patient.
- Is Casey awake?
- Still in recovery.
He doesn't know his surgery failed.
But that's not even
his biggest problem.
We've been analyzing the cells
from the tumor biopsy.
We just finished the RNA sequencing.
WATSON: Is this the right sample?
SASHA: We quadruple-checked.
Look at the end of the RNA sequence.
- Should have a poly(A) tail.
- A short string of A's.
WATSON: There are some G's, too.
SASHA: Not to mention it's long.
Too long.
A tail like this
couldn't occur naturally.
Which suggests genetic modification.
Somebody messed with Casey's genes.
This is genetic tinkering.
Casey's cancer was man-made.
He's sick because
someone made him sick.
I had a mate who died
like that cancer.
Ol' Tom Dinkle.
Smoker from the age of ten.
But that's not what you mean
when you say "man-made," is it?
No, cancer can come
from genetic predisposition,
exposure to carcinogens,
a lifetime of bad habits.
This this is different.
If I sequence a typical cancer cell,
its genetics would be random,
a shuffled card deck.
Casey's cancer isn't shuffled.
It's uniform. It's engineered.
Meaning?
Meaning his disease is the result
of a deliberate genetic modification.
What's fascinating
and, frankly, nightmarish
is that these cells seem to be
I don't know, unkillable?
We treated these cells
with a full round of chemo.
Zero effect.
Like the bad guy from a horror movie.
CASEY: So I still have cancer,
I can't move any of my limbs,
and you're saying
someone did this to me?
Well, I can't speak
to the larger issues,
but as for the paralysis,
you're still in the window
of post-surgery swelling.
Is this Erin Brockovich stuff?
Did I live under
the wrong power lines,
sip the wrong water?
No, this is something else:
gene editing.
Somebody hacked your genome
and gave you a form of cancer
that, as far as we can tell,
is impervious to existing treatment.
What?
How?
That's what we're hoping
you can help us with.
If you haven't voluntarily submitted
to a procedure
that would alter your genes
I mean, did I volunteer
to get immortal cancer?
No, of course I didn't.
Then someone did this
without you knowing about it.
Have you had any injections
recently, a blood draw?
Any medical procedure
could give us a handhold.
I-I don't even know where
to start with all that.
I'm basically a human guinea pig.
Uh, what does that mean?
After I lost my scholarship,
I had two different
call center jobs
that got sent overseas.
Data entry that lasts
as long as it lasts,
server gigs that go away
when the restaurant closes.
And in between all that,
I sign up for studies.
Medical trials.
Sleep stuff, consumer products,
anything that pays the bills.
How many studies?
I don't know.
A few a year for a few years.
Any of these studies
involve gene editing?
Not that they said.
Not that I remember.
But I don't always read
the terms and conditions.
ADAM: Remind me never to
sign another release form again.
SASHA: You can't just slip
"man-made cancer" into the fine print.
I mean, I don't read those things.
- Does anyone?
- (PHONE VIBRATING)
Casey's tested food dyes,
hair products.
He did a sleep deprivation study
at Pitt.
Man, this is bleak.
Not all of us have rich parents.
Nice jacket, by the way.
They're comfortable.
I got one for everyone.
I don't wear my boss's merch,
but thanks.
Come on, leave Adams alone.
Let's just focus on the studies.
- Adams?
- (PHONE VIBRATING)
WATSON: Any trial at a university
or a big company would be regulated.
But Casey said that he participated
in some privately funded studies.
- Let's start there.
- How?
Where would he keep his records?
He has a car, right?
He said it's parked
in his friend's driveway.
He had her move it when he came
here so it wouldn't get towed.
- Okay, go there.
- (PHONE VIBRATING)
See what you can find. Crofts?
Sit with Casey. When he wakes up,
see if you can get a more
- detailed history.
- (PHONE VIBRATING)
Is that our Neanderthal sugar daddy?
I'm pretty sure we're
contractually forbidden
from saying that word.
Is that our secretly Neanderthal
sugar daddy?
WATSON: I wish.
It's our other sugar daddy.
MYCROFT (OVER COMPUTER):
Punctuality, Dr. Watson.
These meetings will be better
for both of us
if we keep to a schedule.
Yeah, we don't need
to check in every day.
In fact, we don't need
to check in at all.
Your brother endowed this clinic
to give me the freedom
to run things my way.
He did that
with money from my company.
We both know that you founded
this company based on his ideas.
His idea would have died
on the vine if not for me.
You obviously have issues
with your brother.
I don't see why my patients
should be in the middle of that.
Had issues, Watson.
One can hardly have issues
with a dead man.
This doesn't have to be adversarial.
I'm not here to close your doors.
No, but you're trying to get
some kind of revenge on your brother,
and I'm never gonna
go along with that.
We were never
particularly close, you know.
I always fancied him a loner,
and then you came along.
You disproved my whole theory.
He just had no interest in me.
So, we will have our daily meeting
and our mutually beneficial
partnership,
even if there are growing pains
along the way.
(CAR DOOR LOCK BEEPS)
(CLICKS TONGUE, SIGHS)
SASHA: Casey tried
to make it like home.
He probably thought his back pain
came from sleeping in the car.
Take the back seat. I got the trunk.
SASHA: Can I ask you something?
A favor, I guess.
I'm listening.
Stephens believes you.
He may have depression.
I'm not a psychiatrist.
He asked me what I thought.
I told him.
That's the thing.
He thinks you're right.
But he won't go see someone
who could actually diagnose him.
- That doesn't make sense.
- Correct.
He'll sit in the morning light.
He signed up to sit
with hospice patients.
But every time I bring up
therapy, he changes the subject.
I'm his girlfriend.
I don't want to be his mom.
And I thought maybe you could
give it the old college try.
Oh, so I get to be his mom?
It's different with you two.
Y'all have something now.
Oh, we have something?
I'm not jealous.
I was just wondering
if you'll talk to him.
Hey, come look at this.
Uh, pay stubs, signed agreements.
Casey kept records.
Have you heard of this place?
Primal BioTech?
- What's that?
- STEPHENS: This is weird.
Primal BioTech website
is full of broken links.
It's pretty much defunct,
as far as I can tell.
Their nondisclosure agreement
is state-of-the-art.
I emailed Lauren.
She says it's unusually dense.
It's way beyond
the standard boilerplate.
Kind of like someone had
something to hide.
What is this place?
Casey remembers two visits
to the same temp office.
First was a blood draw.
Then, three weeks later, an IV drip.
A lab tech said it was
a vitamin supplement
tailored to his genome.
A global search of Casey's email
shows that Primal BioTech
sent 57 follow-up questionnaires
over a span of two months.
The email replies
just bounce back now.
This is a shell company.
They conducted one study
and then vanished
- without a trace.
- WATSON: He did leave a trace.
It was there the whole time.
It takes real arrogance
to sign your work.
What are you talking about, Watson?
I'm talking about Casey's genome.
Take a look and see what's coded
on the RNA tail sequence.
"AAG." Anti-Aging Generation.
The company that got Casey sick
is owned by Joseph Bell.
So, one man comes to us for treatment,
desperate for
whatever help he can get,
another hires us on
but just as the latest
in an endless list
of luxury purchases,
and you're saying, guv,
that they're connected?
That Casey's sick
because of Joseph Bell?
Remember what Sherlock said:
"The universe is rarely so lazy."
The clinic it's the spoke
in a giant wheel
made of medical science
and cutting-edge innovation.
Now, of course,
both of them wound up here.
I mean, it was the only place
they could wind up.
Sasha, tell us what happened.
Casey signed up for a study.
Joseph's people injected him
with whatever,
an editing agent
that turned on a specific gene,
one meant to boost longevity and
squeeze out a few more years.
They didn't set out
to give him cancer.
That's just how it turned out.
What happens now?
I assume Casey can sue Joseph
if he wants to.
If he can find a lawyer
who can crack
those terms and conditions.
Oh, no contract in the world
can cover death by accidental cancer.
Yeah, but does it matter?
Casey's dying.
Money can't help with that.
Whatever it was
that Joseph gave Casey,
we need it.
We need to find it
and we need to study it.
If this cancer can be caused
by genetic manipulation,
then we can work with that.
If Bell even still has the stuff.
Joseph Bell wants to live forever.
If he can't have that,
he'll settle for 20 extra years.
Somewhere inside that compound,
we will find what we're looking for.
So we just walk inside Bell's estate,
poke around without drawing suspicion?
No. He's gonna invite us inside.
As soon as I put up
this post, message
I'm sorry, what am I supposed
to call one of these things?
You're signing up to social media?
Yeah, just for now.
So interesting to learn
that @TheJosephBellAAG
is part Neanderthal.
These titans of the tundra
are the ultimate survivors.
MARY: Go, Neanderthals.
@TheJosephBellAAG repping
the smooth-brained titans
of the tundra.
INGRID: Hey, guys. Neanderthals rock.
@TheJosephBellAAG,
let's go on a quest for fire.
(INDISTINCT OVERLAPPING VOICES)
That's an A-plus
on the thumbs-up test.
(CHUCKLES) That's a good sign, right?
It's a great sign.
It means your swelling is down.
For now, rest, we'll continue
to monitor your progress,
but I'm optimistic
you will regain full function.
So lasting paralysis is off the table?
It is.
I'm really happy for you, Casey.
Just in time to die, though, right?
We're working on a treatment, Casey.
We haven't given up.
Yeah, well, what if this
doesn't work out?
Right, how much do I have
coming to me?
I mean, if this study kills me at 23,
at least I'll be rich, right?
You can't be rich and also dead.
I mean, come on. Can I at least pick?
I wish it worked out that way.
I really do.
(TAKES DEEP BREATH)
What the hey, boys?
Half the Internet's
calling me a caveman.
"Caveman-" that's actually
not accurate.
Well, like I said,
accurate don't matter
when the whole world is clowning you.
You're right. It's my bad.
I get lost in my head sometimes.
I'll delete the post.
No, it's already been re-shared
60,000 times.
Hmm.
How about we give the world
something else to talk about?
Telomere lengthening.
That's where we tweak the ends
of your chromosomes.
Now, if you want to add
some extra years
to your lifespan, that's the real.
I'm down.
Now, you're sure?
'Cause this is gene editing work.
Am I sure?
(GIGGLES) Yeah.
I'm not just vitamins
and cold plunges.
I'm trying to get revolutionary.
Safe and legal just means
slow and boring,
so LFG, buddy.
Jack me up if you dare.
Joseph, after your blood draw,
we should replenish your fluids
with an IV.
I brought a baseline solution,
but I assume you have your own.
Yeah, I don't put anything
baseline in my body.
Not when I have a medical supply room
tailored to my exact genome.
I mean, why should you?
I mean, it's a good point.
(LAUGHING): Exactly. Exactly, John.
- Yeah, yeah.
- JOSEPH: Thank you. I agree.
Hey, Ranger, why don't you show
Dr. Croft the inner sanctum?
RANGER: Mr. Bell
calls this the longevity bunker.
"Mr. Bell"? You can't call him Joseph?
I'm pretty sure he likes "Mr. Bell."
(KEYPAD BEEPING)
Okay.
♪
(SHINWELL SPEAKS INDISTINCTLY)
(RANGER SPEAKS INDISTINCTLY)
SHINWELL: I don't know.
Life's a bit short to be looking
after someone you don't like.
Nursing school.
Tell me about that. What's that like?
SHINWELL: You've done your research.
Well, this kind of work,
it has a ceiling, right?
You've turned it into something else.
- SHINWELL: Hmm.
- RANGER: You know,
I was a medic in my unit.
I'd say that puts you
ahead of the game.
- RANGER: Oh, yeah?
- Yeah.
RANGER: Figured as much.
SHINWELL: Swing down
to the clinic sometime
- without him.
- Absolutely, I'll do that.
And there we are.
The poison apple.
Casey's illness began
when the contents
of this vial got into his system.
If we do our jobs right,
this is what can save him.
You want to make a small
interfering RNA treatment
from one sample?
We can do it.
We can make an off switch
designed specifically
to target Casey's cancer.
I get it, siRNA is
the future of medicine,
but this hasn't been widely tested.
There are a million variables.
You're wondering what we do
if it doesn't work.
- I'm asking a question.
- Well, if it doesn't work,
then he dies, obviously.
That's happening anyway.
Casey's cancer comes from
a single gene manipulation.
This is the perfect test case
for the treatment.
Can anyone tell me why?
SiRNA gets inside the cancer cells,
sends them a message to self-destruct.
It's kind of poetic
if you think about it.
How do you kill an immortal cancer?
- You make it kill itself.
- (DOOR OPENS)
STEPHENS: Watson.
I ran the samples you took
from Joseph Bell.
They tested them against
the markers you requested.
And?
JOSEPH:
I think you have this backwards.
I'm not really on call
to show up wherever you want.
Shh. Quiet, please.
My patient's asleep.
This is Casey Zink.
You don't know him,
but he has a tumor in his spine.
That's terrible. He's so young.
He signed up for a trial with
a company called Primal BioTech.
They put something in his IV.
It was a genome tweak meant
to extend the human lifespan.
Instead, he got cancer.
You did it, Joseph. You did it.
I mean, you created something
that just won't die.
Unfortunately, it's not you.
It's this cancer.
(CHUCKLES) What is this?
I've never heard the name Casey Zink
- in my entire life.
- Yeah, of course not.
There's probably five layers
between you and Casey.
But he's the one that
your shell company ran tests on.
He's dying because of what you did.
(SCOFFS)
- You're fired.
- You might not want to leave.
I have some more news for you,
brother.
Now, you, your company or whoever,
you sent Casey some follow-up surveys.
He reported no side effects.
You don't strike me as a patient man.
So when he said he was fine,
I'm guessing that
you gave yourself
exactly what you gave him
and probably more than one dose.
Am I right?
Nothing you're saying is accurate.
I acknowledge nothing.
I admit nothing.
Dr. Watson?
- Good morning, Casey.
- Morning.
This is Joseph Bell.
He created a company
called Primal BioTech.
He's the one that made you sick.
- JOSEPH: No.
- What?
That's not true. It's not true.
And, see, here's the thing
he is also sick himself.
Joseph infused himself
with the same thing he gave you.
And we checked his markers.
He doesn't know it yet,
but he's very, very ill.
Joseph has cancer, too.
No. (CHUCKLES) No.
I'm Joseph Bell.
I have the liver of a 22-year-old.
You've got cancer, Joseph.
A very unique
and difficult-to-treat form of cancer.
No. No.
It's in your spine.
I understand this is a lot to take in,
and I encourage you to get
a second opinion if you'd like.
I have my blood read
every single morning.
Yeah, but they're not
looking for these
very specific tumor markers.
We did.
We have a treatment.
If you're interested,
I'd say right now
my clinic is the only place
in the world that can help you.
You said the cells can't be killed.
They can be convinced
to kill themselves.
We developed an siRNA treatment.
Casey's already getting it.
If you want,
we can do the same for you.
I'm your doctor,
just like I'm Casey's doctor.
Yeah, of course I want it.
If I'm really sick,
of course I want it.
Why would you even ask me that?
What are you gonna do for Casey Zink?
I'm already paying for his treatment.
What else do you want from me?
He has you dead to rights.
You created Primal BioTech.
You gave him cancer.
So you say.
So I know.
I'm the only person
in the entire world
that could be your doctor.
There's a sick kid in this room
who has cancer because of you.
As far as I'm concerned,
whatever he wants from you, you do it.
(CHUCKLES)
Or else?
I can only take so many patients.
It takes time, you know,
to find the right person.
At first, they sent me
to therapists, psychiatrists.
Then I found a few on my own.
Most are very easy to manipulate.
Now I have one who helps.
And it does help.
I'm never doing talk therapy.
Okay.
Why, though?
You're a scientist. There's data.
Stephens Croft the Fourth
didn't do much
with everything life handed to him.
You're a Fifth?
Stephens Four was
a very good club tennis player
and not much else.
He smiled a lot.
And he was depressed as hell.
After the divorce, he went to maybe
four psychiatrists that I knew about.
The last one got really close to him.
Conversations day and night.
It was weird,
but he said it was helping.
Then he crashed his car on Cape Cod.
Died in the helicopter
on the way to the hospital.
And those things are connected?
Maybe not, maybe yes.
It was an accident.
Unless it wasn't.
What do you think?
I've never said this to Adam.
Not to Sasha, not to anyone.
I don't think that wreck
was an accident.
I think my dad did it on purpose.
I'm never going to therapy.
Stephens.
I'm sorry about what happened
to your dad.
Okay, whatever it was, I'm sorry.
You've never said this to anyone.
Why say it to me?
Because you understand.
(DOOR OPENS, CLOSES)
Thank you so much for coming.
No problem.
Uh
I have to be honest, though,
I am a little nervous.
You'll be fine.
Just sit with her. Watch her shows.
(TV PLAYING INDISTINCTLY)
You okay?
I have a hair appointment.
It's been a while.
Of course.
Do what you need to.
We'll make it.
(CHUCKLES SOFTLY)
You have my number if you need me.
Mm-hmm.
(PICKS UP KEYS)
(DOOR OPENS)
(DOOR CLOSES)
RUTH: Who are you?
Um
My name is Stephens Croft.
I'm here in case you need anything.
I'm here to spend time with you.
That's good.
I'm glad.
Still doing rounds today, sir?
"Sir" ain't necessary.
And I don't do rounds.
I shadow people doing rounds.
Okay, you're still shadowing
people doing rounds?
I am indeed.
Tell you what.
You hang a few feet back,
you observe all you like.
Thank you, sir.
(HANDS CLASP)
Thank you, Shinwell.
That's a weird name.
Yeah yeah yeah yeah,
yeah yeah yeah yeah ♪
Yeah yeah yeah yeah,
yeah yeah yeah ♪
Yeah yeah yeah yeah,
yeah yeah yeah yeah ♪
- (KNOCK AT DOOR)
- (DOOR OPENS)
("THE YEAH YEAH YEAH SONG"
BY THE FLAMING LIPS PLAYING)
WATSON: Doing great, Casey.
Your cells are really responding
to the treatment.
I got lawyers coming by later.
It's like
you know, everyone wants
to know me all of a sudden.
Yeah, that's because
you're money in the bank.
You're gonna make it,
and you're gonna get
everything you want.
You should start thinking about
what you're gonna do with it.
Who are you gonna be now, Casey?
These numbers they're not good.
I know.
Your cancer is mutating too fast
for the treatment to take hold.
My lawyers are giving that kid
everything he asked for.
We're playing ball.
It's not like paying a fine.
This isn't something you can control.
Look, I'm sorry.
We're gonna keep trying,
but you really should be
in the hospital.
With all your power ♪
With all your power ♪
With all your power ♪
What would you do? ♪
With all your power ♪
With all your power ♪
With all your power ♪
What would you do? ♪
- (CAR LOCK BEEPING)
- With all your power ♪
(ENGINE REVVING)
It's okay.
With all your power ♪
With all your power ♪
(FLATLINE BEEP)
What would you do? ♪
(SONG ENDS)
Hello?
Mycroft.
That's my desk.
Did you pay for it?
Get up, or it won't be lawyers
solving our problems.
I can give you what you want.
I can make myself scarce.
I can leave you to run this
clinic under your own auspices.
Very good. Thank you. Goodbye.
You haven't heard me out.
You need to give me
something in return.
My company is reeling.
The formula that my brother left,
it doesn't work the way that
he said it would in the will.
Sherlock did this, Dr. Watson.
He left a poison pill behind
to wreck everything I built
in both our names.
I don't know anything about that.
I think you do.
Sherlock's alive.
He has to be.
He's watching somewhere,
he's laughing.
Tell me I'm right.
Tell me my brother's still alive.
Tell me where he is.
Tell me what I need to know,
and I will withdraw
from your business directly.
I'll leave you alone.
Where is Sherlock Holmes?
("FLASH OF THE BLADE"
BY IRON MAIDEN PLAYING)
sync & corrections awaqeded