Doc (US) (2025) s02e21 Episode Script
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1
(JOAN): Previously on Doc.
You've been different since
you came back from Chicago.
You've changed since this
whole thing with Rachel.
I am Chief now of your department.
You lied on our
first day working together.
I appreciate you
finding a way to trust me.
I'm never gonna trust you, Richard.
(JOAN): You lied for Dr. Miller.
That's the thing about your reputation,
you only have one and once you lose it,
it's almost impossible to get it back.
What could I do at this point?
Find your voice.
Are you alright?
I told her if she wants
to come forward to HR,
we would both have her back.
- Good morning.
- Hey.
- Hey.
- Oh, I'm sweaty.
That's okay,
I like you when you're sweaty.
I can think of a better
way to get you there.
Yeah, but your way means
I can't focus on my lancet.
And I need to brush up
because today is the first day
shadowing my Chief Resident.
Well, I think you're gonna do just fine.
- Coffee?
- Yeah.
Hey, so, Rachel's coming
by the hospital later.
Her biopsy site's not healing well,
so I just wanna, you know, play it safe.
Makes sense. Thanks for telling me.
(CELLPHONE BUZZING)
Michael.
I'll get the coffee.
Morning.
Just wanted to let you know,
Liz filed an HR complaint
against Richard
for coercing her to be part
of last year's cover-up.
As she should,
but hasn't Dixon been
pretty well litigated?
She wasn't party to those agreements.
She's uncomfortable with his
return and I'm supporting her.
And how's he taking it?
(MICHAEL): He doesn't know yet.
I'm giving you the heads up first,
cause adversity doesn't
bring out the best in him.
That's an understatement!
I appreciate you, uh,
looking out for me.
(MICHAEL): Oh, here he is now, gotta go.
Liz is going after Richard with HR.
That'd certainly be poetic justice.
That guy has nine lives.
I'm not holding my breath.
Just have her call me back
after she's out of the deposition,
and let her know that it's important.
Thank you.
(SIGHS)
Dr. Miller?
I got your CBC back,
and your counts are trending
in the right direction.
So, I finally made bail.
Not quite.
Come on, it's been three days, I'm fine!
That's because you've got EPO
and half our blood bank in your system.
(KNOCKING ON DOOR)
Oh, I have her platelets.
Just give it to me,
I'll hang it. Thank you.
So she came forward.
Amy put her up to it, I'm sure.
Nope, that was me.
And I prefer to call it empowering her.
Was that before or after
I saved your life?
You did what you did.
Well, it is great to have you
back in fighting shape, Joan.
I'll check on you in a few hours.
Mr. Zweig.
I'm Dr. Larsen, this is Dr. Heller.
Nice necklace you got there.
Big believer in life.
Aren't we all?
Elevated blood sugar's
blurring his vision.
I got my driver's test coming up.
Drove himself to the hospital,
he's got a 90th birthday party
he's trying to get to this afternoon.
Yeah, yeah, I know, I know, 90.
But don't even think about
taking my keys!
I tried CGM, insulin pump;
he's still hyperglycemic.
You should add a
(CLEARS THROAT)
Um, have you thought about sugar input?
Oh, his diet's pretty good.
I cut latkes and babkas over Covid.
Traded them in for a Peloton.
(AMY): It's not just about what he eats,
it's how it gets into his system.
A glucose absorption blocker
would limit the sugar
entering his blood.
(AMY): Hmm
But it blocks the digoxin
uptake as well.
Right. Bad for the heart.
We reduce glucose reabsorption
in his kidney.
SGLT2 inhibitor.
Great. That sound good to you?
Well, I don't question the plan.
That's how I got this far!
Uh, the pancoast tumor,
it's gonna have to wait
till I get back, I don't trust
Mullins to get clean margins.
And have Gorman cover the cath lab.
No, no, he'll complain, but he'll do it.
I'll call you back for the rest.
Alright.
Hey, morning. I'm Dr. Heller,
this is Dr. Amy
Amy Larsen! Dr. Ben Grant.
I saw you speak at
the osteomyelitis symposium
three years ago
when we hosted in New York.
Sorry I, I wouldn't remember that.
I know. I heard about your accident.
You did?
Yeah, you're pretty
famous on the circuit.
So, we didn't actually meet.
No, I wouldn't, I wouldn't say that.
I challenged you on
non-operative management
of diabetic ulcers,
and you ripped me a new one
in front of a hundred other surgeons.
Yep, that sounds about right!
Thanks a lot!
(LAUGHTER)
So, Renee, Dr. Barrett
said you had questions
about our treatment
of your neuropathic pain?
Not me, my overbearing brother here!
I prefer overprotective.
Dr. Barrett prescribed
300 of gabapentin,
but Renee was on that
when she first got diagnosed,
and it made her too lethargic.
So I'd like to try naltrexone.
There can be significant
GI upset with that.
- Lovely.
- Can you mitigate it?
- Umm
- We could add dichloroacetate,
try split dosing?
Thank you.
- Nice to see you.
- You too.
Again.
What's going on?
His O2's a little low.
Might have something to do with the fact
that he missed his sessions last week!
George! You know dialysis
isn't optional!
I know, but Angie was out of town.
And if I leave the dog alone too long,
she poops on the carpet.
That's why I have cats!
Blood pressure's a little low, too.
You feeling light headed at all?
Tired, achy, slight fever, too.
And why am I just hearing about it?
Figured it was just the toxins
building up in my system.
Should we run additional bloodwork?
Obviously. Yes, Lucy, thank you.
- Mr. Santiago.
- Hey.
I hear you've got a migraine?
Yeah, my head is, is killing me.
Excuse me one minute.
(PHONE BUZZING)
Tell me the terms of
my agreement covers this!
It's a bit of a gray area, I'm afraid.
How could you not have negotiated that?
You wanted back in fast.
And I did not want to raise a red flag
that would have involved her union.
So now what?
I suggest you try to make nice.
No, I can't.
Michael explicitly said that I
need to stay away from her.
Then this is going to
be a very long road.
Code Blue! Code Blue!
We need help in here!
I gotta go!
(PA SYSTEM): Code Blue. Code Blue.
Richard clearly made a mistake
and we need an autopsy.
The patient was in
end-stage renal failure.
A cardiac event
is hardly a surprising twist.
Something is off, Michael.
I looked at his chart,
his anion gap is over 30.
Delayed dialysis
is a perfectly reasonable explanation.
So what, Richard takes a call,
just as his patient codes and dies?
What does that remind you of?
Gina said the code was handled
correctly, so did Liz.
I'm not talking about the code,
I'm talking about
what led up to the code.
I can't be the only one
who thinks that there's
something to be
concerned about here. Jake?
Personally, I don't think
the death was suspicious,
but yes, Richard does have a history
of making mistakes when he's distracted.
When the patient's wife returns my call,
I will ask about an autopsy.
But I don't make any promises.
You made your point, he heard you. Okay?
Let's let Michael do his job,
we do ours.
Mm-hmm.
Herman's ready to be discharged.
Can you handle that?
- Mm-hmm.
- Okay.
(VOMITING)
Sorry.
(CLEARS THROAT)
Onions.
So you just found him like this?
Yes, we got worried when
he missed the house meeting.
Was that before or after you
made him streak the commons?
Our fraternity doesn't haze.
(LAUGHTER) Spare me the BS,
he's a freshman
with a blood alcohol of. 18!
Hey, Dr. Maitra. Got a sec?
Excuse me.
Richard's not giving you
a hard time, is he?
It, it's not that.
Um, did you hear the code?
I think he might have
killed another patient.
What?
I was told not to process the body
cause there may be an autopsy.
(GROANS)
It's just a minor infection, but it's
a good thing you caught it early.
My catastrophic thinking
finally pays off!
Let's just call it vigilance.
Amy okay that I'm here?
I saw her in the hall,
her wave was a little tentative.
Yeah, she wasn't thrilled
that I kept your situation
from her that whole week.
Guess I put you in a tough spot.
And now I'm back again!
It's fine, we're fine.
Yeah?
The doctor who gaslit her, he's back,
and it looks like he
mishandled a patient.
Gaslit her?
He took advantage of her memory loss
and tried to pin
a patient's death on her.
Always a bit of a rollercoaster.
Still,
you're allowed to have
separate nervous systems.
Yeah. This shouldn't take long,
and I will check in on you
when I'm free, okay?
Have you ever seen a dialysis catheter
cause cardiac tamponade?
No, why?
So you're saying it's not possible?
Well, theoretically,
if the tip eroded the wall of the SVC.
- Take a look.
- Richard's patient?
Mm-hmm.
It's not the catheter.
But something's causing bleeding.
His BUN is 95, maybe that
caused platelet dysfunction.
(JEANNIE): Pathology?
Hey, Jeannie, I'm calling
about George Baker.
Do you still have any of his blood?
(JEANNIE): Two vials.
Great. Can you run
a quick PFA? I'll hold.
- Hey.
- Hey!
Is there a problem with Herman Zweig?
Uh
He's still here.
Oh! I forgot to discharge him.
Seems like you forgot him altogether
because you're here chasing Richard.
- I'm sorry.
- Your world.
- We just live in it.
- Hey!
(SIGHS)
I'm sorry, but you did
see his tattoo, right?
- Yeah.
- Okay.
I was just hoping that maybe
you'd go above and beyond
for someone like that.
It's fine, I'll discharge him myself.
He's got family waiting
to celebrate his 90th.
(JEANNIE): Okay, got your results.
Um, is his platelet function prolonged?
(JEANNIE): Nope, normal.
His coags are through the roof, though.
I mean, bananas high!
Richard was right, it wasn't his fault.
- Well, that's a relief.
- No, not really.
I think George Baker
had a hemorrhagic fever.
(SCOFFS)
Come on!
Flu-like symptoms,
low BP, sky-high coags
and D-dimer AST, triple ALT.
That is a hemorrhagic viral picture.
Had he been travelling recently?
No, but Lucy said that his wife
just got back from a safari in Tanzania.
Did you talk to her?
I've been trying for hours,
she hasn't been answering.
Public Health needs to get
to her house, with HAZMATs
and you need to lock down this floor!
Amy, I
I know, you're gonna wanna test
and do an autopsy,
but every minute that passes,
somebody who may have been
exposed leaves this building
and they spread it.
We can't blink, Michael.
They were both in the code
with Richard and Gina.
- Go find them and isolate them.
- Okay.
(SPEAKER BEEPING)
Attention, Code Five.
Attention, Code Five!
All individuals are asked
to shelter in place,
I repeat, all individuals,
shelter in place!
(MICHAEL): George Baker tested positive
for a variant of Marburg.
Which, as you know,
has a very mortality rate
and is extremely contagious.
It has characteristics
of the 2005 Angola outbreak,
and the 2012 Uganda outbreak,
but it is unique.
Dr. Franco is doing an autopsy now
and I have Dr. Larsen sequencing
the virus as we speak.
I'm liaising with the CDC,
and as of now, Baker is the only
confirmed case in Minneapolis,
though Public Health
is checking on his wife.
In the meantime,
containment is our priority.
Nobody in, nobody out.
Wait here.
Those with symptoms
or high risk exposures
will be isolated and observed.
Dr. Walker, Dr. Miller, Liz and Lucy
were exposed during the code
and we are waiting on
the results of their tests.
We will test ourselves
and our patients every 12 hours.
Confirmed cases will be
quarantined in the ICU,
which, from here on out,
you do not enter without HAZMAT gear.
Decontaminate upon exit.
Gloves and gowns will suffice
for regular patient care,
but we need to minimize interaction.
If it can wait, it should wait.
What about emergent situations?
Handled on a case-by-case basis.
My patient in 623
may need a Graham patch.
This is Dr. Grant, Chair of
Cardio-Thoracics
at St. Mark's in New York.
Double boarded in trauma,
he had the misfortune
of being here today.
I'm happy to help in any way I can.
If surgery is needed,
Dr. Coleman will assist,
and Dr. Douglas,
you good with anesthesia?
I can push drugs and keep
a heart pumping.
Yeah, but where? We've got
people in every patient room.
Waiting rooms are being sterilized.
I can work anywhere.
We're all gonna have to improvise today,
but we can do this.
Oh, absolutely.
Joan, you can't be out of your room!
I am content to sit
in here and contact trace,
I suspect I'm the only one
here who's actually done it?
I'll get you security cam footage.
The rest of you, I need you room to room
to collect blood samples
and answer questions.
So, the whole floor's infected?
No, no.
The lockdown is a precaution,
and it's not airborne.
It's spread through fluid droplets,
person-to-person and on the surface,
which is why you need
to stay in your room.
- For how long?
- Days?
I can't be in here for days,
my mother depends on me
for full-time care.
Is there someone else you can call?
My father's a lawyer
and just so you know,
he won't stand for you holding me here.
Fever, chills, chest pain,
nausea, even a headache,
you let us know.
Meantime, I'm gonna need
blood samples to test you.
I suggest you cooperate.
I'm really sorry you're trapped
in here today of all days.
You still serve food? Then I'm good!
You can't just lock us in here!
My wife is waiting downstairs!
The lockdown is for your protection.
Oh yeah, that's what the
geniuses said last time,
and then it was two years
of us hiding from a flu!
Hey. Hey!
You'll go where they say,
or you and me are gonna have a problem.
What a crock!
I already talked to Allie,
she said she can look after Mia
until this is over.
You really don't know how long
this is gonna be?
I mean, once I'm negative,
I can go home
It doesn't work like that, negative
could just mean not positive yet.
I want you to take your
temperature every hour.
If it's over 99, you call me.
I'll have your tests results
on this in a bit, okay?
Jake?
You seem scared.
I am.
(TENSE MUSIC)
Just tell the boys that I'm okay,
and I'll be home as soon as I can.
I'm testing negative right now,
but um,
I don't think I'll be in the
clear for a couple of days.
Welcome to the world's worst sleepover.
I saved you the top bunk!
Doubt I'll be doing much sleeping.
I don't have privacy right now,
so I can't talk about that.
Yeah, okay.
I love you too.
Kind of puts all of our other problems
into perspective, doesn't it?
(LAUGHS)
Okay, can someone catch me up?
I filed an HR complaint,
not that it matters now.
Where's Lucy?
Maybe they're still waiting
for her test results to come back.
She got Mr. Baker's blood
on her face during the code.
I know.
(SIGHS)
(JULIE): I know it's hard, ma'am,
but you do need to
isolate from your kids.
No, if you try to get on
a plane, police will intervene.
Well, I wish you had better news,
but I appreciate the update.
Yeah, I'll send over addresses
for anyone else we can't find.
Thanks.
Public Health just found
Mrs. Baker, dead in her home.
I assume they'll get their own
contact tracing unit up and running.
Yeah. In the meantime,
we've identified 27
of the 39 individuals
who left the floor.
Make that 28.
And we've also mapped out
George Baker's movements
through the sixth floor,
identifying any hotspots we can.
Restroom, sign-in tablet,
anything he touched or coughed on.
We'll need a list of anyone
who had high exposure to these areas.
We're scrubbing the footage
to ID whomever we can.
Our code team's the real problem.
I thought they were already
isolated in the on-call room.
All but Lucy, who just tested positive.
So the incubation
period's hours, not days.
Even Ebola's not that fast!
And the code team was moving
freely before the lockdown began.
You're saying Liz, Dr. Miller
and Dr. Walker are
definitely carrying it?
Not necessarily,
but to be safe, we need
to isolate their patients.
Alright, so, we got 627 cleared,
so let's go and isolate
Mr. Batal in there.
And Sammy, can you get Rachel in 619?
- We're gonna need her room too.
- On it.
Dad, there's gotta be
something you can do!
Whoa, you're bringing
someone else in here?
We need to create isolation
spaces for people
who have confirmed exposures.
Be grateful you're not one of them.
But is that safe?
Stick to your side of the room,
don't touch anything on his side.
If they give you any trouble,
let me know, I will be back.
I can take care of myself,
Doc. I'm good here.
We're gonna figure this out, Lucy. Okay?
(SOFT MUSIC)
(AMY): Michael, can you hear m?
Yeah, you have an update?
(AMY): We got the autopsy report.
You're gonna want to see this.
Liver necrosis, splenic rupture,
bleeding bowel. Lungs, kidneys.
- All liquefied.
- Baker was a dead man walking.
Anything from the sequencing?
(AMY): This surface GP substitution
accelerates transmission.
And the VP3 mutation,
and the high MPC1 affinity
mean rapid cell entry.
So, it's even more lethal
than conventional Marburg?
And twice as contagious as Ebola.
(TENSE MUSIC)
(HEAVY BREATHING)
Any change?
BP's dipping. If fluid resus
doesn't work, we need to escalate.
I'm so cold.
It's the fever,
I'll get IV acetaminophen
and a warm blanket.
You hanging in there?
My temp was 103,
my sats are all over the place.
I've seen worse.
And your kidneys
are still humming along.
(COUGHING)
Can I take a look?
(COUGHING)
Let's see.
She has petechiae
on the roof of her mouth.
She's lactate. Full coags, ABG.
I'll get the kit.
I'll type and cross four units of blood.
I'm so scared, Amy!
I know, Lucy!
I'm just glad it's you
taking care of me.
I just wanna hold his hand, please!
We got another one.
Dr. Larsen, we're running out of space.
- Is that
- George Baker's roommate.
Gina's patient?
(TENSE MUSIC)
(CELLPHONE CHIMES)
(SIGHS)
Now what?
Carl Santiago just tested positive.
Lucy worked on both of them.
So did I!
Don't think like that, Liz.
If I hadn't distracted you today,
would you have caught this earlier?
I didn't catch anything. Amy did.
He couldn't be saved, Liz.
And he exposed everybody
the second he stepped on this floor.
I just wanted things
to go back to normal.
(SIGHS)
Liz.
For whatever it's worth,
you didn't deserve
everything I put you through.
And I am sorry.
How's Lucy?
We're doing everything we can.
What about you two, still no fever?
We're all good in here!
As of an hour ago.
Go ahead and take your
temperature again.
- Jake!
- Rache, just, take it again.
See?
Nothing to worry about in here,
except a low phone battery.
And, maybe a mild case of PTSD.
(JAKE): How's that?
Talking through a window?
It's like 2020 all over again,
except I'm you,
sleeping in the garage.
Try doing it for months.
Oh yeah, that horrible air mattress.
Anyway, let me see if I can
go find you a phone charger.
My hero!
(SOFT MUSIC)
Hard to be in here, huh?
When the person you love is
on the wrong side of the door.
Oh, we're not, Jake's my ex.
Still family.
(DR. GRANT): Tell me if this
is tender, okay?
(GROANS)
- That's a yes!
- Okay.
(COUGHING)
Sorry. The ulcer acts up
when I get stressed.
I'm sorry but your pressure's dropping
and you're losing too much blood,
I'm worried about perforation.
(CELLPHONE BUZZING)
Just a sec.
About time you called me back!
How's Mom? Did you get her dinner?
Ella, I need you to put
the phone down and listen to me.
We have to operate on your ulcer.
Now?
(MACHINE BEEPS)
Dr. Coleman! We've got a job to
do, and we're gonna do it well.
- Are you ready?
- Yes sir!
Inspiration, please.
(SUNNY BY BOBBY HEBB PLAYS)
Scalpel.
Yesterday my life
was filled with rain ♪♪♪
(PHONE): They really can't tell
you how long you'll be there?
- Dude, just stop.
- But why should he get the bed?
He's been sleeping all day.
You know how these things are.
They're just being extra careful, hey!
You think that's funny?
(PHONE): What's going on there, Dad?
Oh, just a jackass born on third base,
thinks he's hit a triple!
Hey, whoa, whoa!
What the hell, what did you do?
Whoa!
He's having a seizure!
Turn him on his side!
I'm not gonna touch him,
he could be infected!
But how? He didn't even leave the room!
- No, he's choking!
- So, one of us has it?
Don't look at me!
- He got you.
- It's gonna be okay.
Hey, Herman! Herman, Herman, Herman.
Hey, give me one gram of kepra,
two migs of lorazepam.
Herman, hey, let's step back,
okay? Let's step back.
Why the hell was he
the one helping your friend?
(JULIE): Lorazepam.
O2 sats dropping, pulmonary edema.
We max out high flow,
and then we tube her.
(COUGHING)
(WHEEZING)
How are the others? Liz?
Everyone's dying,
I can't do this anymore.
Um, they're okay.
Try to rest.
Okay, I got one.
Would you rather work an overnight shift
and it's just enemas all night,
or go to a wedding as Peter's plus one?
Uhh, do I have to dance with him?
Two songs.
Yeah, I'll take the enemas!
(GINA): Too easy.
(LIZ): I mean, you've seen him
do the robot
at the holiday party,
would you dance with him?
(GINA): Fair point.
- You alright?
- Stay away from me.
It's Dr. Miller.
I need to be tested.
She's third-spacing everywhere.
Julie, hang two more units, and an FFP!
Her blood's thinning out.
(DOOR OPENING)
Richard.
Gina's still negative. So is Liz.
The ventilators aren't working!
(ECG BEEPING)
- You can let go now.
- Code blue!
Hemothorax. Amy?
Yep, I'll do a needle thoracentesis.
- DIC?
- Yeah.
Rapid infuser. Now!
(TENSE MUSIC)
She's in hypovolemic shock!
We're gonna get through this, Amy!
I want every unit we have
on hand in that infuser!
(LONG BEEP)
Pushing epi.
I'll start compressions!
(LONG BEEP)
Charge to 120.
Amy, Amy. It's no use.
She's gone.
(LONG BEEP)
(HEAVY BREATHING)
(SOBBING)
(BEEPING STOPS)
Time of death, 22:47.
(SOBBING)
(SOFT MUSIC)
Still can't believe she's gone.
Mr. Santiago, too.
This thing goes south fast, TJ.
I'm taking your ICU shift, okay?
You go deal with my patients.
I'm in a position of leadership now,
I'm not handing off my work!
Hey. Part of being a leader
is admitting when you need help
and trusting the people
around you to share the load.
Downshift for a couple of hours.
We got a long road here.
(EQUIPMENT BEEPING)
(HEAVY BREATHING)
(CELLPHONE BUZZING)
Hey.
(AMY): Step back from the door, okay?
Uh, I'm not near it. Why?
I didn't want you to be alone.
I'm sure I'll see you
in ICU soon enough.
- Don't say that!
- Am I wrong?
Did you talk to Wendy?
She's taking it like a champ! So far.
How's Katie?
She's pretty Pollyanna, actually.
Which is good, given,
you know, everything she's been through.
I just wish I could be
out there helping you all.
I'm sure seeing Lucy
like that was terrible.
No.
(SHOUTING AND COUGHING)
Was that a memory seizure?
Of Covid.
Seems like trauma brings back trauma.
There's always phenobarb.
No, it has so many
potential side effects.
Promise me you'll be careful.
I love you.
Back at ya!
(SOFT MUSIC)
(MICHAEL): I'm looking at
the material you sent,
but this doesn't help me.
Our strain is way more aggressive
than whatever you're
tracking in Tanzania.
I can't just hit it with Remdesivir.
What about other antivirals?
So you're telling me supportive care
is your best advice?
I mean, Eastside lost
two more this morning.
Great. Well, when you
have a better idea,
you know where to find me!
Guessing you slept almost
as well as I did last night.
Thank you.
I was prepared to treat the patients.
Not our people.
And I can't look anyone in the eye
and tell them this is going to be okay.
I think George Baker
went to the vending machines
before treatment.
It's the only other place the
college kids went on the sixth floor.
And I missed it.
We don't even have cameras there.
No, but when he returned
to his patient room at 9:23,
he had a soda in his hand.
If I'd isolated based on that criteria,
we'd be in much better shape.
We've been playing catch up
since the beginning, Joan.
Yeah. Yeah.
Hey!
I'll be right back, okay?
(MACHINES BEEPING)
Why isn't any of this working?
Sir, we are doing everything we can.
Well, it's not good enough!
No, don't touch me,
you just touched him!
I cannot give you
something you already have!
Now please, let me examine you.
- Hey Jules!
- Yeah?
You see this much
lymphadenopathy in other patients?
Uh, I'm not sure.
Hey, I have a lump, too.
It's replicating fast.
Wait, why do you say
that like it's a good thing?
Its speed is its weakness.
Accelerated multiplication
makes the virus prone to errors.
And open to attack,
by replication-inhibiting antivirals.
Okay yeah, but which one?
I mean, cardiac failure in bed
two points to protease inhibitors,
but respiratory failure in seven
suggests neuramidase inhibitors
might be more effective.
- We could design our own.
- You wanna invent an antiviral?
A cocktail, based on what we know
about the virus's components
from genetic sequencing.
Toremifene destabilizes
viral glycoprotein.
Interferon beta-1a
inhibits VP3 expression.
And cathepsin-B would definitely
interfere with NPC1 binding.
It's still doesn't address
your replication rate.
It would if we added a
nucleoside analog to slow it down.
There are gonna be a lot of variables.
Yeah. We all have to step
outside of our comfort zones
if we want to attack this.
She's right. Mix and match,
try finding a combination that gives us
the most bang for our buck.
Or, we could sit back,
manage symptoms and pray.
As you know, this infection
can get very serious very quickly.
And we won't wait for that to happen.
We have designed four drug
cocktails we believe could help.
So, you're improvising?
We ran a sophisticated analysis.
What if your analysis is wrong?
All volunteers will
be closely monitored.
Negative responses will be
met with immediate intervention.
So if you screw up,
then we have to trust you to fix it.
That is an oversimplification.
I mean, they have a test!
How can they not have
a decent treatment?
Oh, so which is it? You think
we're incompetent?
Or gods?
Or just liars, for some unknown reason?
Not helping.
You're under no obligation.
And yes, there are serious risks.
(SHOUTING)
Liver failure, heart attack, even death.
(JAKE): We're running out of space!
Code blue!
But you'll learn something
either way, right?
I'm in.
Thank you, Richard. Anyone else?
Come on. You wanna just
lie around here, hoping?
Or do you wanna fight back?
(EMOTIONAL MUSIC)
Good. We'll get started shortly.
Hey. Are you having memories?
I just need a minute.
(LOUD CHAOTIC SOUNDS)
(HEAVY BREATHING)
Uh, hi!
Hey. It'd be good if we can
get a PCR up here for us.
They're working on that.
I heard you blew Dr. Coleman away
with your surgical skills
and your playlist.
It's nothing compared
to what you're doing.
It's not exactly
the best way to meet again.
(LUCY): We're gonna
get through this, Amy.
You alright?
I just yeah.
Yeah, I'm fine.
Oh. I'm gonna go check on Ella, post-op.
(TENSE MUSIC)
(TENSE MUSIC)
Liz? Did the ondansetron
help with the nausea?
Not yet.
Alright, I'm going to
try adding haloperidol.
How are you feeling?
Any shortness of breath?
Only since Y2K!
Remember, the world was
supposed to come to an end then?
Yeah, it seems kind
of quaint now, doesn't it?
I'll be alright, Doc. Really.
Well, you let me know
if that changes, okay?
Yeah.
How's he doing?
His O2 sats are falling.
He never should have been in
the room with those asshats.
We're in triage, we had no choice.
How are your patients doing?
I think Kenny needs a cardiac echo,
and Layla's showing signs
of systemic inflammation.
Okay, I'll take a look, in the meantime,
can you get Audrey started
on parenteral support?
Got it.
(AMY): We're almost at capacity here.
Yeah, and the hits keep coming.
How's Gina?
She's still negative and asymptomatic.
Somehow.
I'll take any good news I can get.
Chase's cerebral edema
didn't respond to mannitol,
so I sedated him.
Herman's putting on a brave face,
but his O2 sats are drifting,
and our resident conspiracy theorist's
getting splenomegaly,
but doesn't believe it.
Dr. Hamda, Dr. Larsen!
Dr. Miller's fever broke!
He was at 104 earlier,
he's down to 101.7
and sats are improving.
His cocktail's working.
Does this mean what I think it means?
We won't know until
we try it on the others.
- Dr. Franco.
- Yes?
How long to get me enough
cocktail number four
for everyone up here?
An hour to reconstitute the vials,
two to balance the infusion solutions
and another to prep the IV bags.
Some of my patients
may not have that long.
We've got extra hands moving in now.
(KATIE): That's such a relief, Mom!
Oh, I know! Believe me.
I gave blood again today.
It's the only thing I can do to help.
You sure you okay? You seem exhausted.
I'm, well, I just need
this coffee to kick in!
Listen, I should get back, I need
Wait, Mom! Promise me if either
of you get sick, I wanna know.
You will.
I love you.
Love you too.
(SIGHS)
(ELEVATOR CHIME)
Let's move, everyone!
Just in time, Chase is unstable.
And Herman's getting more tachycardic.
Thank you.
(AMY): Thanks. Oh!
You okay?
Yeah, I'm just running on empty.
Going once, going twice?
No thanks, use it on your guinea pigs!
Besides, your friend?
He don't look so good.
(GRUNTING)
Julie, blood check on Richard!
(GROANING)
It feels like
AST's 13,000!
What?
Michael! Fulminant hepatic failure!
(GROANING)
Peaked Ts, that's hyperkalemia.
He's gonna code!
V-fib!
(EQUIPMENT BEEPING)
- Epi's in.
- Charging to 200!
Clear!
(BEEPING)
Okay.
There's no bleeding.
This isn't the hemorrhagic fever.
It's a drug reaction.
Everyone, stop the infusions!
O2 sats are dropping.
TJ, check his lungs!
(JULIE): I'm drawing up the steroids.
(MICHAEL): Starting high flow oxygen.
We're losing him again!
Tension pneumo!
We need to decompress.
Okay.
You're almost in.
(MACHINE BEEPING)
- Sats are coming up.
- I've got the hub.
Pull the needle.
Oh!
Oh no, no, no!
(TENSE MUSIC)
Needle stick protocol.
What's going on? What's happened?
(MICHAEL): She got stuck
with an infected needle.
Dr. Heller, get her out of here!
Disinfect, test and isolate. Stat!
Ray! Step in!
TJ, get on the chest tube. Now!
(TENSE MUSIC)
(TENSE MUSIC)
(BEEPING)
(TENSE MUSIC CONTINUES)
(THEME MUSIC)
(JOAN): Previously on Doc.
You've been different since
you came back from Chicago.
You've changed since this
whole thing with Rachel.
I am Chief now of your department.
You lied on our
first day working together.
I appreciate you
finding a way to trust me.
I'm never gonna trust you, Richard.
(JOAN): You lied for Dr. Miller.
That's the thing about your reputation,
you only have one and once you lose it,
it's almost impossible to get it back.
What could I do at this point?
Find your voice.
Are you alright?
I told her if she wants
to come forward to HR,
we would both have her back.
- Good morning.
- Hey.
- Hey.
- Oh, I'm sweaty.
That's okay,
I like you when you're sweaty.
I can think of a better
way to get you there.
Yeah, but your way means
I can't focus on my lancet.
And I need to brush up
because today is the first day
shadowing my Chief Resident.
Well, I think you're gonna do just fine.
- Coffee?
- Yeah.
Hey, so, Rachel's coming
by the hospital later.
Her biopsy site's not healing well,
so I just wanna, you know, play it safe.
Makes sense. Thanks for telling me.
(CELLPHONE BUZZING)
Michael.
I'll get the coffee.
Morning.
Just wanted to let you know,
Liz filed an HR complaint
against Richard
for coercing her to be part
of last year's cover-up.
As she should,
but hasn't Dixon been
pretty well litigated?
She wasn't party to those agreements.
She's uncomfortable with his
return and I'm supporting her.
And how's he taking it?
(MICHAEL): He doesn't know yet.
I'm giving you the heads up first,
cause adversity doesn't
bring out the best in him.
That's an understatement!
I appreciate you, uh,
looking out for me.
(MICHAEL): Oh, here he is now, gotta go.
Liz is going after Richard with HR.
That'd certainly be poetic justice.
That guy has nine lives.
I'm not holding my breath.
Just have her call me back
after she's out of the deposition,
and let her know that it's important.
Thank you.
(SIGHS)
Dr. Miller?
I got your CBC back,
and your counts are trending
in the right direction.
So, I finally made bail.
Not quite.
Come on, it's been three days, I'm fine!
That's because you've got EPO
and half our blood bank in your system.
(KNOCKING ON DOOR)
Oh, I have her platelets.
Just give it to me,
I'll hang it. Thank you.
So she came forward.
Amy put her up to it, I'm sure.
Nope, that was me.
And I prefer to call it empowering her.
Was that before or after
I saved your life?
You did what you did.
Well, it is great to have you
back in fighting shape, Joan.
I'll check on you in a few hours.
Mr. Zweig.
I'm Dr. Larsen, this is Dr. Heller.
Nice necklace you got there.
Big believer in life.
Aren't we all?
Elevated blood sugar's
blurring his vision.
I got my driver's test coming up.
Drove himself to the hospital,
he's got a 90th birthday party
he's trying to get to this afternoon.
Yeah, yeah, I know, I know, 90.
But don't even think about
taking my keys!
I tried CGM, insulin pump;
he's still hyperglycemic.
You should add a
(CLEARS THROAT)
Um, have you thought about sugar input?
Oh, his diet's pretty good.
I cut latkes and babkas over Covid.
Traded them in for a Peloton.
(AMY): It's not just about what he eats,
it's how it gets into his system.
A glucose absorption blocker
would limit the sugar
entering his blood.
(AMY): Hmm
But it blocks the digoxin
uptake as well.
Right. Bad for the heart.
We reduce glucose reabsorption
in his kidney.
SGLT2 inhibitor.
Great. That sound good to you?
Well, I don't question the plan.
That's how I got this far!
Uh, the pancoast tumor,
it's gonna have to wait
till I get back, I don't trust
Mullins to get clean margins.
And have Gorman cover the cath lab.
No, no, he'll complain, but he'll do it.
I'll call you back for the rest.
Alright.
Hey, morning. I'm Dr. Heller,
this is Dr. Amy
Amy Larsen! Dr. Ben Grant.
I saw you speak at
the osteomyelitis symposium
three years ago
when we hosted in New York.
Sorry I, I wouldn't remember that.
I know. I heard about your accident.
You did?
Yeah, you're pretty
famous on the circuit.
So, we didn't actually meet.
No, I wouldn't, I wouldn't say that.
I challenged you on
non-operative management
of diabetic ulcers,
and you ripped me a new one
in front of a hundred other surgeons.
Yep, that sounds about right!
Thanks a lot!
(LAUGHTER)
So, Renee, Dr. Barrett
said you had questions
about our treatment
of your neuropathic pain?
Not me, my overbearing brother here!
I prefer overprotective.
Dr. Barrett prescribed
300 of gabapentin,
but Renee was on that
when she first got diagnosed,
and it made her too lethargic.
So I'd like to try naltrexone.
There can be significant
GI upset with that.
- Lovely.
- Can you mitigate it?
- Umm
- We could add dichloroacetate,
try split dosing?
Thank you.
- Nice to see you.
- You too.
Again.
What's going on?
His O2's a little low.
Might have something to do with the fact
that he missed his sessions last week!
George! You know dialysis
isn't optional!
I know, but Angie was out of town.
And if I leave the dog alone too long,
she poops on the carpet.
That's why I have cats!
Blood pressure's a little low, too.
You feeling light headed at all?
Tired, achy, slight fever, too.
And why am I just hearing about it?
Figured it was just the toxins
building up in my system.
Should we run additional bloodwork?
Obviously. Yes, Lucy, thank you.
- Mr. Santiago.
- Hey.
I hear you've got a migraine?
Yeah, my head is, is killing me.
Excuse me one minute.
(PHONE BUZZING)
Tell me the terms of
my agreement covers this!
It's a bit of a gray area, I'm afraid.
How could you not have negotiated that?
You wanted back in fast.
And I did not want to raise a red flag
that would have involved her union.
So now what?
I suggest you try to make nice.
No, I can't.
Michael explicitly said that I
need to stay away from her.
Then this is going to
be a very long road.
Code Blue! Code Blue!
We need help in here!
I gotta go!
(PA SYSTEM): Code Blue. Code Blue.
Richard clearly made a mistake
and we need an autopsy.
The patient was in
end-stage renal failure.
A cardiac event
is hardly a surprising twist.
Something is off, Michael.
I looked at his chart,
his anion gap is over 30.
Delayed dialysis
is a perfectly reasonable explanation.
So what, Richard takes a call,
just as his patient codes and dies?
What does that remind you of?
Gina said the code was handled
correctly, so did Liz.
I'm not talking about the code,
I'm talking about
what led up to the code.
I can't be the only one
who thinks that there's
something to be
concerned about here. Jake?
Personally, I don't think
the death was suspicious,
but yes, Richard does have a history
of making mistakes when he's distracted.
When the patient's wife returns my call,
I will ask about an autopsy.
But I don't make any promises.
You made your point, he heard you. Okay?
Let's let Michael do his job,
we do ours.
Mm-hmm.
Herman's ready to be discharged.
Can you handle that?
- Mm-hmm.
- Okay.
(VOMITING)
Sorry.
(CLEARS THROAT)
Onions.
So you just found him like this?
Yes, we got worried when
he missed the house meeting.
Was that before or after you
made him streak the commons?
Our fraternity doesn't haze.
(LAUGHTER) Spare me the BS,
he's a freshman
with a blood alcohol of. 18!
Hey, Dr. Maitra. Got a sec?
Excuse me.
Richard's not giving you
a hard time, is he?
It, it's not that.
Um, did you hear the code?
I think he might have
killed another patient.
What?
I was told not to process the body
cause there may be an autopsy.
(GROANS)
It's just a minor infection, but it's
a good thing you caught it early.
My catastrophic thinking
finally pays off!
Let's just call it vigilance.
Amy okay that I'm here?
I saw her in the hall,
her wave was a little tentative.
Yeah, she wasn't thrilled
that I kept your situation
from her that whole week.
Guess I put you in a tough spot.
And now I'm back again!
It's fine, we're fine.
Yeah?
The doctor who gaslit her, he's back,
and it looks like he
mishandled a patient.
Gaslit her?
He took advantage of her memory loss
and tried to pin
a patient's death on her.
Always a bit of a rollercoaster.
Still,
you're allowed to have
separate nervous systems.
Yeah. This shouldn't take long,
and I will check in on you
when I'm free, okay?
Have you ever seen a dialysis catheter
cause cardiac tamponade?
No, why?
So you're saying it's not possible?
Well, theoretically,
if the tip eroded the wall of the SVC.
- Take a look.
- Richard's patient?
Mm-hmm.
It's not the catheter.
But something's causing bleeding.
His BUN is 95, maybe that
caused platelet dysfunction.
(JEANNIE): Pathology?
Hey, Jeannie, I'm calling
about George Baker.
Do you still have any of his blood?
(JEANNIE): Two vials.
Great. Can you run
a quick PFA? I'll hold.
- Hey.
- Hey!
Is there a problem with Herman Zweig?
Uh
He's still here.
Oh! I forgot to discharge him.
Seems like you forgot him altogether
because you're here chasing Richard.
- I'm sorry.
- Your world.
- We just live in it.
- Hey!
(SIGHS)
I'm sorry, but you did
see his tattoo, right?
- Yeah.
- Okay.
I was just hoping that maybe
you'd go above and beyond
for someone like that.
It's fine, I'll discharge him myself.
He's got family waiting
to celebrate his 90th.
(JEANNIE): Okay, got your results.
Um, is his platelet function prolonged?
(JEANNIE): Nope, normal.
His coags are through the roof, though.
I mean, bananas high!
Richard was right, it wasn't his fault.
- Well, that's a relief.
- No, not really.
I think George Baker
had a hemorrhagic fever.
(SCOFFS)
Come on!
Flu-like symptoms,
low BP, sky-high coags
and D-dimer AST, triple ALT.
That is a hemorrhagic viral picture.
Had he been travelling recently?
No, but Lucy said that his wife
just got back from a safari in Tanzania.
Did you talk to her?
I've been trying for hours,
she hasn't been answering.
Public Health needs to get
to her house, with HAZMATs
and you need to lock down this floor!
Amy, I
I know, you're gonna wanna test
and do an autopsy,
but every minute that passes,
somebody who may have been
exposed leaves this building
and they spread it.
We can't blink, Michael.
They were both in the code
with Richard and Gina.
- Go find them and isolate them.
- Okay.
(SPEAKER BEEPING)
Attention, Code Five.
Attention, Code Five!
All individuals are asked
to shelter in place,
I repeat, all individuals,
shelter in place!
(MICHAEL): George Baker tested positive
for a variant of Marburg.
Which, as you know,
has a very mortality rate
and is extremely contagious.
It has characteristics
of the 2005 Angola outbreak,
and the 2012 Uganda outbreak,
but it is unique.
Dr. Franco is doing an autopsy now
and I have Dr. Larsen sequencing
the virus as we speak.
I'm liaising with the CDC,
and as of now, Baker is the only
confirmed case in Minneapolis,
though Public Health
is checking on his wife.
In the meantime,
containment is our priority.
Nobody in, nobody out.
Wait here.
Those with symptoms
or high risk exposures
will be isolated and observed.
Dr. Walker, Dr. Miller, Liz and Lucy
were exposed during the code
and we are waiting on
the results of their tests.
We will test ourselves
and our patients every 12 hours.
Confirmed cases will be
quarantined in the ICU,
which, from here on out,
you do not enter without HAZMAT gear.
Decontaminate upon exit.
Gloves and gowns will suffice
for regular patient care,
but we need to minimize interaction.
If it can wait, it should wait.
What about emergent situations?
Handled on a case-by-case basis.
My patient in 623
may need a Graham patch.
This is Dr. Grant, Chair of
Cardio-Thoracics
at St. Mark's in New York.
Double boarded in trauma,
he had the misfortune
of being here today.
I'm happy to help in any way I can.
If surgery is needed,
Dr. Coleman will assist,
and Dr. Douglas,
you good with anesthesia?
I can push drugs and keep
a heart pumping.
Yeah, but where? We've got
people in every patient room.
Waiting rooms are being sterilized.
I can work anywhere.
We're all gonna have to improvise today,
but we can do this.
Oh, absolutely.
Joan, you can't be out of your room!
I am content to sit
in here and contact trace,
I suspect I'm the only one
here who's actually done it?
I'll get you security cam footage.
The rest of you, I need you room to room
to collect blood samples
and answer questions.
So, the whole floor's infected?
No, no.
The lockdown is a precaution,
and it's not airborne.
It's spread through fluid droplets,
person-to-person and on the surface,
which is why you need
to stay in your room.
- For how long?
- Days?
I can't be in here for days,
my mother depends on me
for full-time care.
Is there someone else you can call?
My father's a lawyer
and just so you know,
he won't stand for you holding me here.
Fever, chills, chest pain,
nausea, even a headache,
you let us know.
Meantime, I'm gonna need
blood samples to test you.
I suggest you cooperate.
I'm really sorry you're trapped
in here today of all days.
You still serve food? Then I'm good!
You can't just lock us in here!
My wife is waiting downstairs!
The lockdown is for your protection.
Oh yeah, that's what the
geniuses said last time,
and then it was two years
of us hiding from a flu!
Hey. Hey!
You'll go where they say,
or you and me are gonna have a problem.
What a crock!
I already talked to Allie,
she said she can look after Mia
until this is over.
You really don't know how long
this is gonna be?
I mean, once I'm negative,
I can go home
It doesn't work like that, negative
could just mean not positive yet.
I want you to take your
temperature every hour.
If it's over 99, you call me.
I'll have your tests results
on this in a bit, okay?
Jake?
You seem scared.
I am.
(TENSE MUSIC)
Just tell the boys that I'm okay,
and I'll be home as soon as I can.
I'm testing negative right now,
but um,
I don't think I'll be in the
clear for a couple of days.
Welcome to the world's worst sleepover.
I saved you the top bunk!
Doubt I'll be doing much sleeping.
I don't have privacy right now,
so I can't talk about that.
Yeah, okay.
I love you too.
Kind of puts all of our other problems
into perspective, doesn't it?
(LAUGHS)
Okay, can someone catch me up?
I filed an HR complaint,
not that it matters now.
Where's Lucy?
Maybe they're still waiting
for her test results to come back.
She got Mr. Baker's blood
on her face during the code.
I know.
(SIGHS)
(JULIE): I know it's hard, ma'am,
but you do need to
isolate from your kids.
No, if you try to get on
a plane, police will intervene.
Well, I wish you had better news,
but I appreciate the update.
Yeah, I'll send over addresses
for anyone else we can't find.
Thanks.
Public Health just found
Mrs. Baker, dead in her home.
I assume they'll get their own
contact tracing unit up and running.
Yeah. In the meantime,
we've identified 27
of the 39 individuals
who left the floor.
Make that 28.
And we've also mapped out
George Baker's movements
through the sixth floor,
identifying any hotspots we can.
Restroom, sign-in tablet,
anything he touched or coughed on.
We'll need a list of anyone
who had high exposure to these areas.
We're scrubbing the footage
to ID whomever we can.
Our code team's the real problem.
I thought they were already
isolated in the on-call room.
All but Lucy, who just tested positive.
So the incubation
period's hours, not days.
Even Ebola's not that fast!
And the code team was moving
freely before the lockdown began.
You're saying Liz, Dr. Miller
and Dr. Walker are
definitely carrying it?
Not necessarily,
but to be safe, we need
to isolate their patients.
Alright, so, we got 627 cleared,
so let's go and isolate
Mr. Batal in there.
And Sammy, can you get Rachel in 619?
- We're gonna need her room too.
- On it.
Dad, there's gotta be
something you can do!
Whoa, you're bringing
someone else in here?
We need to create isolation
spaces for people
who have confirmed exposures.
Be grateful you're not one of them.
But is that safe?
Stick to your side of the room,
don't touch anything on his side.
If they give you any trouble,
let me know, I will be back.
I can take care of myself,
Doc. I'm good here.
We're gonna figure this out, Lucy. Okay?
(SOFT MUSIC)
(AMY): Michael, can you hear m?
Yeah, you have an update?
(AMY): We got the autopsy report.
You're gonna want to see this.
Liver necrosis, splenic rupture,
bleeding bowel. Lungs, kidneys.
- All liquefied.
- Baker was a dead man walking.
Anything from the sequencing?
(AMY): This surface GP substitution
accelerates transmission.
And the VP3 mutation,
and the high MPC1 affinity
mean rapid cell entry.
So, it's even more lethal
than conventional Marburg?
And twice as contagious as Ebola.
(TENSE MUSIC)
(HEAVY BREATHING)
Any change?
BP's dipping. If fluid resus
doesn't work, we need to escalate.
I'm so cold.
It's the fever,
I'll get IV acetaminophen
and a warm blanket.
You hanging in there?
My temp was 103,
my sats are all over the place.
I've seen worse.
And your kidneys
are still humming along.
(COUGHING)
Can I take a look?
(COUGHING)
Let's see.
She has petechiae
on the roof of her mouth.
She's lactate. Full coags, ABG.
I'll get the kit.
I'll type and cross four units of blood.
I'm so scared, Amy!
I know, Lucy!
I'm just glad it's you
taking care of me.
I just wanna hold his hand, please!
We got another one.
Dr. Larsen, we're running out of space.
- Is that
- George Baker's roommate.
Gina's patient?
(TENSE MUSIC)
(CELLPHONE CHIMES)
(SIGHS)
Now what?
Carl Santiago just tested positive.
Lucy worked on both of them.
So did I!
Don't think like that, Liz.
If I hadn't distracted you today,
would you have caught this earlier?
I didn't catch anything. Amy did.
He couldn't be saved, Liz.
And he exposed everybody
the second he stepped on this floor.
I just wanted things
to go back to normal.
(SIGHS)
Liz.
For whatever it's worth,
you didn't deserve
everything I put you through.
And I am sorry.
How's Lucy?
We're doing everything we can.
What about you two, still no fever?
We're all good in here!
As of an hour ago.
Go ahead and take your
temperature again.
- Jake!
- Rache, just, take it again.
See?
Nothing to worry about in here,
except a low phone battery.
And, maybe a mild case of PTSD.
(JAKE): How's that?
Talking through a window?
It's like 2020 all over again,
except I'm you,
sleeping in the garage.
Try doing it for months.
Oh yeah, that horrible air mattress.
Anyway, let me see if I can
go find you a phone charger.
My hero!
(SOFT MUSIC)
Hard to be in here, huh?
When the person you love is
on the wrong side of the door.
Oh, we're not, Jake's my ex.
Still family.
(DR. GRANT): Tell me if this
is tender, okay?
(GROANS)
- That's a yes!
- Okay.
(COUGHING)
Sorry. The ulcer acts up
when I get stressed.
I'm sorry but your pressure's dropping
and you're losing too much blood,
I'm worried about perforation.
(CELLPHONE BUZZING)
Just a sec.
About time you called me back!
How's Mom? Did you get her dinner?
Ella, I need you to put
the phone down and listen to me.
We have to operate on your ulcer.
Now?
(MACHINE BEEPS)
Dr. Coleman! We've got a job to
do, and we're gonna do it well.
- Are you ready?
- Yes sir!
Inspiration, please.
(SUNNY BY BOBBY HEBB PLAYS)
Scalpel.
Yesterday my life
was filled with rain ♪♪♪
(PHONE): They really can't tell
you how long you'll be there?
- Dude, just stop.
- But why should he get the bed?
He's been sleeping all day.
You know how these things are.
They're just being extra careful, hey!
You think that's funny?
(PHONE): What's going on there, Dad?
Oh, just a jackass born on third base,
thinks he's hit a triple!
Hey, whoa, whoa!
What the hell, what did you do?
Whoa!
He's having a seizure!
Turn him on his side!
I'm not gonna touch him,
he could be infected!
But how? He didn't even leave the room!
- No, he's choking!
- So, one of us has it?
Don't look at me!
- He got you.
- It's gonna be okay.
Hey, Herman! Herman, Herman, Herman.
Hey, give me one gram of kepra,
two migs of lorazepam.
Herman, hey, let's step back,
okay? Let's step back.
Why the hell was he
the one helping your friend?
(JULIE): Lorazepam.
O2 sats dropping, pulmonary edema.
We max out high flow,
and then we tube her.
(COUGHING)
(WHEEZING)
How are the others? Liz?
Everyone's dying,
I can't do this anymore.
Um, they're okay.
Try to rest.
Okay, I got one.
Would you rather work an overnight shift
and it's just enemas all night,
or go to a wedding as Peter's plus one?
Uhh, do I have to dance with him?
Two songs.
Yeah, I'll take the enemas!
(GINA): Too easy.
(LIZ): I mean, you've seen him
do the robot
at the holiday party,
would you dance with him?
(GINA): Fair point.
- You alright?
- Stay away from me.
It's Dr. Miller.
I need to be tested.
She's third-spacing everywhere.
Julie, hang two more units, and an FFP!
Her blood's thinning out.
(DOOR OPENING)
Richard.
Gina's still negative. So is Liz.
The ventilators aren't working!
(ECG BEEPING)
- You can let go now.
- Code blue!
Hemothorax. Amy?
Yep, I'll do a needle thoracentesis.
- DIC?
- Yeah.
Rapid infuser. Now!
(TENSE MUSIC)
She's in hypovolemic shock!
We're gonna get through this, Amy!
I want every unit we have
on hand in that infuser!
(LONG BEEP)
Pushing epi.
I'll start compressions!
(LONG BEEP)
Charge to 120.
Amy, Amy. It's no use.
She's gone.
(LONG BEEP)
(HEAVY BREATHING)
(SOBBING)
(BEEPING STOPS)
Time of death, 22:47.
(SOBBING)
(SOFT MUSIC)
Still can't believe she's gone.
Mr. Santiago, too.
This thing goes south fast, TJ.
I'm taking your ICU shift, okay?
You go deal with my patients.
I'm in a position of leadership now,
I'm not handing off my work!
Hey. Part of being a leader
is admitting when you need help
and trusting the people
around you to share the load.
Downshift for a couple of hours.
We got a long road here.
(EQUIPMENT BEEPING)
(HEAVY BREATHING)
(CELLPHONE BUZZING)
Hey.
(AMY): Step back from the door, okay?
Uh, I'm not near it. Why?
I didn't want you to be alone.
I'm sure I'll see you
in ICU soon enough.
- Don't say that!
- Am I wrong?
Did you talk to Wendy?
She's taking it like a champ! So far.
How's Katie?
She's pretty Pollyanna, actually.
Which is good, given,
you know, everything she's been through.
I just wish I could be
out there helping you all.
I'm sure seeing Lucy
like that was terrible.
No.
(SHOUTING AND COUGHING)
Was that a memory seizure?
Of Covid.
Seems like trauma brings back trauma.
There's always phenobarb.
No, it has so many
potential side effects.
Promise me you'll be careful.
I love you.
Back at ya!
(SOFT MUSIC)
(MICHAEL): I'm looking at
the material you sent,
but this doesn't help me.
Our strain is way more aggressive
than whatever you're
tracking in Tanzania.
I can't just hit it with Remdesivir.
What about other antivirals?
So you're telling me supportive care
is your best advice?
I mean, Eastside lost
two more this morning.
Great. Well, when you
have a better idea,
you know where to find me!
Guessing you slept almost
as well as I did last night.
Thank you.
I was prepared to treat the patients.
Not our people.
And I can't look anyone in the eye
and tell them this is going to be okay.
I think George Baker
went to the vending machines
before treatment.
It's the only other place the
college kids went on the sixth floor.
And I missed it.
We don't even have cameras there.
No, but when he returned
to his patient room at 9:23,
he had a soda in his hand.
If I'd isolated based on that criteria,
we'd be in much better shape.
We've been playing catch up
since the beginning, Joan.
Yeah. Yeah.
Hey!
I'll be right back, okay?
(MACHINES BEEPING)
Why isn't any of this working?
Sir, we are doing everything we can.
Well, it's not good enough!
No, don't touch me,
you just touched him!
I cannot give you
something you already have!
Now please, let me examine you.
- Hey Jules!
- Yeah?
You see this much
lymphadenopathy in other patients?
Uh, I'm not sure.
Hey, I have a lump, too.
It's replicating fast.
Wait, why do you say
that like it's a good thing?
Its speed is its weakness.
Accelerated multiplication
makes the virus prone to errors.
And open to attack,
by replication-inhibiting antivirals.
Okay yeah, but which one?
I mean, cardiac failure in bed
two points to protease inhibitors,
but respiratory failure in seven
suggests neuramidase inhibitors
might be more effective.
- We could design our own.
- You wanna invent an antiviral?
A cocktail, based on what we know
about the virus's components
from genetic sequencing.
Toremifene destabilizes
viral glycoprotein.
Interferon beta-1a
inhibits VP3 expression.
And cathepsin-B would definitely
interfere with NPC1 binding.
It's still doesn't address
your replication rate.
It would if we added a
nucleoside analog to slow it down.
There are gonna be a lot of variables.
Yeah. We all have to step
outside of our comfort zones
if we want to attack this.
She's right. Mix and match,
try finding a combination that gives us
the most bang for our buck.
Or, we could sit back,
manage symptoms and pray.
As you know, this infection
can get very serious very quickly.
And we won't wait for that to happen.
We have designed four drug
cocktails we believe could help.
So, you're improvising?
We ran a sophisticated analysis.
What if your analysis is wrong?
All volunteers will
be closely monitored.
Negative responses will be
met with immediate intervention.
So if you screw up,
then we have to trust you to fix it.
That is an oversimplification.
I mean, they have a test!
How can they not have
a decent treatment?
Oh, so which is it? You think
we're incompetent?
Or gods?
Or just liars, for some unknown reason?
Not helping.
You're under no obligation.
And yes, there are serious risks.
(SHOUTING)
Liver failure, heart attack, even death.
(JAKE): We're running out of space!
Code blue!
But you'll learn something
either way, right?
I'm in.
Thank you, Richard. Anyone else?
Come on. You wanna just
lie around here, hoping?
Or do you wanna fight back?
(EMOTIONAL MUSIC)
Good. We'll get started shortly.
Hey. Are you having memories?
I just need a minute.
(LOUD CHAOTIC SOUNDS)
(HEAVY BREATHING)
Uh, hi!
Hey. It'd be good if we can
get a PCR up here for us.
They're working on that.
I heard you blew Dr. Coleman away
with your surgical skills
and your playlist.
It's nothing compared
to what you're doing.
It's not exactly
the best way to meet again.
(LUCY): We're gonna
get through this, Amy.
You alright?
I just yeah.
Yeah, I'm fine.
Oh. I'm gonna go check on Ella, post-op.
(TENSE MUSIC)
(TENSE MUSIC)
Liz? Did the ondansetron
help with the nausea?
Not yet.
Alright, I'm going to
try adding haloperidol.
How are you feeling?
Any shortness of breath?
Only since Y2K!
Remember, the world was
supposed to come to an end then?
Yeah, it seems kind
of quaint now, doesn't it?
I'll be alright, Doc. Really.
Well, you let me know
if that changes, okay?
Yeah.
How's he doing?
His O2 sats are falling.
He never should have been in
the room with those asshats.
We're in triage, we had no choice.
How are your patients doing?
I think Kenny needs a cardiac echo,
and Layla's showing signs
of systemic inflammation.
Okay, I'll take a look, in the meantime,
can you get Audrey started
on parenteral support?
Got it.
(AMY): We're almost at capacity here.
Yeah, and the hits keep coming.
How's Gina?
She's still negative and asymptomatic.
Somehow.
I'll take any good news I can get.
Chase's cerebral edema
didn't respond to mannitol,
so I sedated him.
Herman's putting on a brave face,
but his O2 sats are drifting,
and our resident conspiracy theorist's
getting splenomegaly,
but doesn't believe it.
Dr. Hamda, Dr. Larsen!
Dr. Miller's fever broke!
He was at 104 earlier,
he's down to 101.7
and sats are improving.
His cocktail's working.
Does this mean what I think it means?
We won't know until
we try it on the others.
- Dr. Franco.
- Yes?
How long to get me enough
cocktail number four
for everyone up here?
An hour to reconstitute the vials,
two to balance the infusion solutions
and another to prep the IV bags.
Some of my patients
may not have that long.
We've got extra hands moving in now.
(KATIE): That's such a relief, Mom!
Oh, I know! Believe me.
I gave blood again today.
It's the only thing I can do to help.
You sure you okay? You seem exhausted.
I'm, well, I just need
this coffee to kick in!
Listen, I should get back, I need
Wait, Mom! Promise me if either
of you get sick, I wanna know.
You will.
I love you.
Love you too.
(SIGHS)
(ELEVATOR CHIME)
Let's move, everyone!
Just in time, Chase is unstable.
And Herman's getting more tachycardic.
Thank you.
(AMY): Thanks. Oh!
You okay?
Yeah, I'm just running on empty.
Going once, going twice?
No thanks, use it on your guinea pigs!
Besides, your friend?
He don't look so good.
(GRUNTING)
Julie, blood check on Richard!
(GROANING)
It feels like
AST's 13,000!
What?
Michael! Fulminant hepatic failure!
(GROANING)
Peaked Ts, that's hyperkalemia.
He's gonna code!
V-fib!
(EQUIPMENT BEEPING)
- Epi's in.
- Charging to 200!
Clear!
(BEEPING)
Okay.
There's no bleeding.
This isn't the hemorrhagic fever.
It's a drug reaction.
Everyone, stop the infusions!
O2 sats are dropping.
TJ, check his lungs!
(JULIE): I'm drawing up the steroids.
(MICHAEL): Starting high flow oxygen.
We're losing him again!
Tension pneumo!
We need to decompress.
Okay.
You're almost in.
(MACHINE BEEPING)
- Sats are coming up.
- I've got the hub.
Pull the needle.
Oh!
Oh no, no, no!
(TENSE MUSIC)
Needle stick protocol.
What's going on? What's happened?
(MICHAEL): She got stuck
with an infected needle.
Dr. Heller, get her out of here!
Disinfect, test and isolate. Stat!
Ray! Step in!
TJ, get on the chest tube. Now!
(TENSE MUSIC)
(TENSE MUSIC)
(BEEPING)
(TENSE MUSIC CONTINUES)
(THEME MUSIC)